Results 271 to 280 of about 4,108,081 (382)

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

CMap: a database for mapping job titles, sector specialization, and promotions across 24 sectors. [PDF]

Sci Data
Subhani S, Memon SA, AlShebli B.
europepmc   +1 more source

The 4th Report on the Study of Abrasion Mechanism of Metals at The Japan Society for the Promotion of Scientific Research : Researches on the Mechanism of Abrasion : Report IV. Relation between Abrasion of Carbon Steel and its Mechanical, Physical and Chemical Properties

, 1943
Makoto OKOSHI, Hideharu SAKAI
openalex   +2 more sources

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

Ganz Salzburg bewegen [All of Salzburg Moving]: a large-scale public involvement project with underserved groups, for the co-design of local and contextualized physical activity promotion concepts. [PDF]

Res Involv Engagem
Kulnik ST, Salbrechter S, Radwanovsky S, Garstenauer U, Ebner M, Fuhrmeister T, Stainer-Hochgatterer A, Wurhofer D, Roth M.   +8 more
europepmc   +1 more source

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee, Keyue Chen, Ryan Loke, Xiang Li, David Liubart, Golam T. Saffi, Jonathan T. S. Chow, Ché M. P. Melo, Lydia To, Leonardo Salmena   +9 more
wiley   +1 more source

Quantitative evaluation of China's adolescent physical activity policies: a PMC Index model approach. [PDF]

Front Public Health
Huang X, Zhang C, Li J, Ding X.
europepmc   +1 more source

Suggestions offered on the part of the Literary and Philosophical Society of Liverpool, to members of the mercantile marine, who may be desirous of using the advantages they enjoy for the promotion of science, in furtherance of zoology

openalex   +2 more sources

ON THE ANALYTICAL METHOD OF NITROGEN IN IRON AND STEEL, PROPOSED BY THE FOUNDATION FOR THE PROMOTION OF THE SCIENCE AND INDUSTRIAL RESEARCH OF JAPAN

, 1936
Kuniichi Tawara
openalex   +2 more sources

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

Molecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan, Moshe Leitner, Amos Toren, Shoshana Paglin, Michal Yalon   +4 more
wiley   +1 more source