Results 111 to 120 of about 4,256,398 (299)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

An evaluation of the Cheshire Sexual Health Promotion project [PDF]

open access: yes, 2005
This project report discusses an evaluation study of the Sexual Health Promotion project in Cheshire, which ran from 2000 to 2004.The project was commissioned by the steering group of the Sexual Health Promotion project and funded by South Cheshire ...
Killey, Mona   +2 more
core   +2 more sources

Connecticut's transportation strategy

open access: yes, 2011
Title from PDF cover (publisher's Web site, viewed Mar. 23, 2011).; "Section 13b-57g, General Statutes of Connecticut"--P. 3.; "January, 2011."; Updates: Moving forward.

core   +1 more source

Sport tourism: regional promotion strategies [PDF]

open access: yes, 2004
The main purposes of this paper are (i) to analyze the regional promotion strategies of the UEFA Euro 2004 and (ii) to contribute for the improvement of planning and implementation strategies of tourism marketing at regional level. Data regarding these strategies were collected and synthesized.
José Cadima Ribeiro   +2 more
openaire   +2 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Defining sustainable practice in community-based health promotion: A Delphi study of practitioner perspectives

open access: yes, 2013
Issue addressed: Sustainability of practice must be a central imperative in the practice of community-based health promotion to achieve population health and attract a greater share of public health spending. Although there has been some consideration of
Harris, Neil   +5 more
core   +1 more source

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