Results 91 to 100 of about 76,110 (378)

Loss of the epithelial transcription factor grhl3 leads to variably penetrant developmental phenotypes in zebrafish

Developmental Dynamics, EarlyView.
Abstract Background Environmental influence is critical for embryogenesis but is significantly under‐appreciated under lab conditions, which are not typically designed to robustly test environmental variability. Here, we report environmental effects on the developmental phenotype of zebrafish lacking the transcription factor Grainyhead‐like 3 (grhl3 ...
Nishanthi Mathiyalagan, Travis K. Johnson, Zachary Di Pastena, Jarrad N. Fuller, Lee B. Miles, Sebastian Dworkin   +5 more
wiley   +1 more source

Patient-reported outcomes following flexible sigmoidoscopy screening for colorectal cancer in a demonstration screening programme in the UK [PDF]

, 2012
<p>OBJECTIVES: Flexible sigmoidoscopy (FS) screening for colorectal cancer will be introduced into the National Cancer Screening Programmes in England in 2013.
Atkin, W., Edwards, R., Kralj-Hans, I., Lo, S.H., Power, E., Robb, K.A., Vance, M., Von Wagner, C., Wardle, J.   +8 more
core   +1 more source

Implementing Nature‐Based Solutions in Cities: Testing and Refining the Integrative Framework for Collaborative Governance

Environmental Policy and Governance, EarlyView.
ABSTRACT Literature highlights the importance of collaborative arrangements in implementing Nature‐Based Solutions (NBS) to address climate change impacts, such as the urban heat island effect. However, very little is known about the design and implementation of such collaborative arrangements.
Evi van Dorsselaer, Joris Voets, Claire Dupont   +2 more
wiley   +1 more source

Introducing Tony Hall's cunning plan: The BB(&A)C [PDF]

, 2014
Tony Hall’s scheme for the BBC’s future has been widely disdained as a willful desire to put the clock back to the days of ‘Auntie’ BBC, but Brian Winston argues it is more like a return to the brilliant deal that acquired the Proms in the ...
Winston, Brian
core  

Prognostic value of NT‐proBNP in patients with primary mitral regurgitation undergoing transcatheter edge‐to‐edge repair

European Journal of Heart Failure, EarlyView.
In the PRIME‐MR study, patients with higher N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP) tertiles more frequently reached death or heart failure hospitalization (HFH) within 3 years. Log‐transformed NT‐proBNP levels independently predicted the primary endpoint (adjusted hazard ratio 1.17, 95% confidence interval 1.07–1.28; p < 0.001).
Philipp von Stein, Jessica Weimann, Roman Pfister, Sebastian Ludwig, Benedikt Koell, Erwan Donal, Dhairya Patel, Lukas Stolz, Tetsu Tanaka, Andrea Scotti, Teresa Trenkwalder, Felix Rudolph, Daryoush Samim, Cristina Giannini, Julien Dreyfus, Jean‐Michel Paradis, Marianna Adamo, Nicole Karam, Yohann Bohbot, Anne Bernard, Bruno Melica, Angelo Quagliana, Yoan Lavie Badie, Mirjam Kessler, Omar Chehab, Simon Redwood, Edith Lubos, Lars Sondergaard, Marco Metra, Chiara Primerano, Fabien Praz, Muhammed Gerçek, Erion Xhepa, Georg Nickenig, Azeem Latib, Niklas Schofer, Raj Makkar, Juan F. Granada, Thomas Modine, Jörg Hausleiter, Augustin Coisne, Daniel Kalbacher, Christos Iliadis, on behalf of the PRIME‐MR Investigators, Paul Achouh, David Attias, Stephan Baldus, Alain Berrebi, Guillaume Bonnet, Laura Granada, Frederic Bouisset, Corentin Bourg, Thierry Bourguignon, Diogo Ferreira, Stéphane Lafitte, Thibault Lhermusier, Guillaume L'official, Mohammed Nejjari, Edoardo Pancaldi, Lydia X. Plewe, Tobias Rheude, Natacha Rousse, Volker Rudolph, Dan Rusinaru, Christophe Saint‐Etienne, Francisco Sampaio, Jury Schewel, Arnaud Sudre, Christophe Tribouilloy, Marcel Weber, Stephan Windecker   +70 more
wiley   +1 more source

The use of patient‐reported outcome measures by healthcare professionals in specialized asthma management centers in French‐speaking Belgium: A mixed‐methods study

Clinical and Translational Allergy, 2023
Introduction Recently, the literature has promoted the use of patient‐reported outcome measures (PROMs) in clinical practice as a means to foster patient engagement.
Gilles Louis, Bernard Voz, Michèle Guillaume, Delphine Kirkove, Benoit Pétré   +4 more
doaj   +1 more source

An emerging framework for fully incorporating public involvement (PI) into patient-reported outcome measures (PROMs)

Journal of Patient-Reported Outcomes, 2020
Patient-reported outcome measures (PROMs) are widely used in the United Kingdom (UK) and internationally to report and monitor patients’ subjective assessments of their symptoms and functional status and also their quality of life.
Jill Carlton, T. Peasgood, S. Khan, Rosemary Barber, J. Bostock, A. Keetharuth   +5 more
semanticscholar   +1 more source

Integration of patient-reported outcome measures with key clinical outcomes after immediate latissimus dorsi breast reconstruction and adjuvant treatment

, 2013
Background: linical evidence on patient-reported outcome measures (PROMS) in breast reconstruction is lacking. The aim of this study was to evaluate PROMs in implant-assisted latissimus dorsi (LDI) or tissue-only autologous latissimus dorsi (ALD) flap ...
Balta, V, Benson, J, Betambeau, N, Haviland, J, Prospective Trial Management, Grp, Reece-Smith, A, Winters, Z. E   +6 more
core   +1 more source

The iBRA (implant breast reconstruction evaluation) study: protocol for a prospective multi-centre cohort study to inform the feasibility, design and conduct of a pragmatic randomised clinical trial comparing new techniques of implant-based breast reconstruction. [PDF]

, 2016
BACKGROUND: Implant-based breast reconstruction (IBBR) is the most commonly performed reconstructive procedure in the UK. The introduction of techniques to augment the subpectoral pocket has revolutionised the procedure, but there is a lack of high ...
Barnes, NL, Blazeby, JM, Branford, OA, Breast Reconstruction Research Collaborative, Conroy, EJ, Cutress, RI, Gardiner, MD, Holcombe, C, Jain, A, McEvoy, K, Mills, N, Mylvaganam, S, Potter, S, Skillman, JM, Teasdale, EM, Thrush, S, Whisker, LJ, Williamson, PR   +17 more
core   +4 more sources

Real world testing and cost‐effectiveness analysis of subcutaneous EEG (REAL‐ASE): Protocol for a prospective multicentre interventional trial

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy is a common condition associated with significant morbidity, mortality, and costs. Poor documentation of seizures is a major challenge in epilepsy care. Objective seizure counting with mobile devices may mitigate this challenge and improve patient management.
Matthew McWilliam, Pedro F. Viana, Eren Dursun, Joe Davies, Joel S. Winston, Jessica Agren, Harutomo Hasegawa, Jonas Duun‐Henriksen, Mark P. Richardson   +8 more
wiley   +1 more source