Background Rare diseases may be life-threatening or chronically debilitating conditions. Patient care needs are often complex and challenging to coordinate and deliver effectively.
O. Aiyegbusi+7 more
semanticscholar +1 more source
Are Patient Self-Reported Outcome Measures Sensitive Enough to Be Used as End Points in Clinical Trials?: Evidence from the United Kingdom Glaucoma Treatment Study [PDF]
Purpose The United Kingdom Glaucoma Treatment Study (UKGTS) demonstrated the effectiveness of an intraocular pressure-lowering drug in patients with glaucoma using visual field progression as a primary outcome.
Amalfitano, F.+25 more
core +1 more source
Physical therapy management, surgical treatment, and patient-reported outcomes measures in a prospective observational cohort of patients with neurogenic thoracic outlet syndrome [PDF]
OBJECTIVE: To assess the results of physical therapy management and surgical treatment in a prospective observational cohort of patients with neurogenic thoracic outlet syndrome (NTOS) using patient-reported outcomes measures. METHODS: Of 183 new patient
Abuirqeba, Ahmmad A+7 more
core +1 more source
The management of segmental tibial shaft fractures: A systematic review. [PDF]
INTRODUCTION: Segmental tibial fractures are complex injuries associated with significant soft tissue damage that are difficult to treat. This study aimed to identify the most effective method of treating segmental tibial fractures.
Hing, CB+4 more
core +1 more source
Abstract Objective To develop and validate advanced machine learning (ML) models for predicting unplanned intrapartum cesarean deliveries in women with no previous cesarean delivery, using both static and dynamic clinical data. Methods A retrospective cohort study was conducted using nationwide data from a large integrated healthcare provider ...
Ido Givon+7 more
wiley +1 more source
Setting a research agenda for progressive multiple sclerosis: The International Collaborative on Progressive MS [PDF]
Despite significant progress in the development of therapies for relapsing MS, progressive MS remains comparatively disappointing. Our objective, in this paper, is to review the current challenges in developing therapies for progressive MS and identify ...
Baker, D+17 more
core +2 more sources
Termination of pregnancy for medical indications: A 14‐year analysis from a tertiary referral center
Abstract Objective This study aimed to evaluate the medical indications for termination of pregnancy, gestational age at termination, and methods used in our clinic. Methods This observational retrospective study included pregnancy terminations after 10 weeks of gestation for medical indications between 2010 and 2024.
Yasemin Dogan+5 more
wiley +1 more source
Nurse-friendly nutritional screening for patient benefit [PDF]
Screening for undernutrition is highly important and may reduce morbidity and mortality. The Minimal Eating Observation and Nutrition Form – Version II (MEONF-II) is a nutritional screening tool specifically developed for use by nurses. Here, we describe
Hagell, Peter+3 more
core +2 more sources
Abstract Objective This large cohort study investigates the impact of premature rupture of membranes (PROM) on maternal and neonatal outcomes in breech deliveries. The aim is to contribute to a better understanding of vaginal breech delivery and its possible risk factors and to facilitate more informed decision‐making within the counseling process ...
Emmy Rasch+6 more
wiley +1 more source
Feedback from activity trackers improves daily step count after knee and hip arthroplasty: A randomized controlled trial [PDF]
Background: Commercial wrist-worn activity monitors have the potential to accurately assess activity levels and are being increasingly adopted in the general population.
Gooden, Benjamin+7 more
core +1 more source