Results 41 to 50 of about 1,036,863 (338)

Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes

FEBS Letters, EarlyView.
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji, Yuko Katayama, Nanase Arata, Mariko Sasaki   +3 more
wiley   +1 more source

Three-dimensional conformal breast irradiation in the prone position

Brazilian Journal of Medical and Biological Research, 2003
The prone position can be used for the planning of adjuvant radiotherapy after conservative breast surgery in order to deliver less irradiation to lung and cardiac tissue.
C. Kurtman, M. Nalça Andrieu, A. Hiçsönmez, B. Çelebioglu   +3 more
doaj   +1 more source

Prolonged prone position in pregnant woman with COVID-19 pneumonia

Journal of Anesthesia, Analgesia and Critical Care, 2022
The manuscript describes a case report of 2 prolonged prone position cycles (72 h each) of a coronavirus disease 2019 pneumonia in an intubated pregnant woman (at 22 weeks of gestational age), being successfully discharged from intensive care unit after ...
Federico Linassi, Matteo Campagnolo, Enrico Busato, Valentina Ortolani, Mario Peta   +4 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Transthoracic echocardiography during prone position ventilation: Lessons from the COVID‐19 pandemic

Journal of the American College of Emergency Physicians Open, 2020
Objective The current coronavirus disease 2019 (COVID‐19 outbreak) demands an increased need for hospitalizations in emergency departments (EDs) and critical care units.
Edgar García‐Cruz, Daniel Manzur‐Sandoval, Rodrigo Gopar‐Nieto, Adriana L. Murillo‐Ochoa, Gabriela Bejarano‐Alva, Gustavo Rojas‐Velasco, Rolando J. Álvarez‐Álvarez, Francisco Baranda‐Tovar   +7 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Prone position therapy from the ICU nurse perspective: an integrated revision [PDF]

, 2015
Introducción: La terapia de posicionamiento decúbito prono es una de las alternativas disponibles en el tratamiento del Síndrome de Distrés Respiratorio Agudo (SDRA) en las unidades de cuidados críticos.
Campello-Vicente, Cristina, Del Saz-Caja, María Inmaculada, Tomás-Robles, Amelia, Vidal-Baños, Antonio, Villaescusa-Carrillo, María Carolina   +4 more
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Anesthesia in the prone lithotomy position [PDF]

Canadian Journal of Anesthesia/Journal canadien d'anesthésie, 2001
To the Editor: We present our experience of the anesthetic management of patients in the rarely used prone lithotomy position (Figure). During surgery, the prone position, if correctly applied, ensures free abdominal movement, is not associated with adverse effects on respiratory mechanics and improves lung volume and oxygenation.1,2 The lithotomy ...
S, Srivastava, C K, Pandey
openaire   +2 more sources