Results 221 to 230 of about 1,488,747 (298)

Report on the proof-of-concept animal studies

Insert at least 3 devices to 3 groups of the models of D2.4 (5-6/group) via burred holes. Groups will receive additional implants as follows:(I) a reprogramming organoid; (II, positive control) iNSC expressing TRAIL (pro-apoptotic). (III, negative control), iNSCs without reprogramming miRNA.
openaire   +1 more source

Laser‐Assisted Processing and Modification of Bioactive Glasses: A Review

Advanced Healthcare Materials, EarlyView.
Laser technologies provide powerful tools to process and transform bioactive glasses for advanced biomedical applications. This review discusses laser‐matter interaction mechanisms, laser surface engineering, and laser‐assisted fabrication of scaffolds and nanofibers.
Antonio Riveiro, Mario González‐Quintas, Mónica Fernández‐Arias, Jesús del Val, Félix Quintero, Rafael Comesaña, Fernando Lusquiños, Julian R. Jones, Juan Pou   +8 more
wiley   +1 more source

Radiomics-Based Prognostication in Primary Sclerosing Cholangitis: A Proof-of-Concept Study. [PDF]

Liver Int
Cristoferi L, Maino C, Bernasconi DP, Ripamonti I, Scaravaglio M, Savino A, Pesatori E, Gerussi A, Nofit E, Falco O, D'Amato D, Gallivanone F, Alberzoni C, Viganò R, Mazzarelli C, Belli LS, Dinelli ME, Mutignani M, Valsecchi MG, Corso R, Invernizzi P, Carbone M, Ippolito D, Bernardi E.   +23 more
europepmc   +1 more source

Modular Control of PEG‐Poly(2‐Oxazoline) Co‐Assembly Enables Tunable Aggregate Properties for Intraocular Pressure Management

Advanced Healthcare Materials, EarlyView.
A thermo‐responsive poly(2‐oxazoline)‐based injectable formulation is developed to modulate intraocular pressure (IOP) in both normal and hypotonic eyes. By adjusting the PEG content, the aggregation behavior is finely tuned, enabling IOP elevation without long‐term deposition.
Yuji Tanaka, Shohei Morikawa, Shigehito Osawa   +2 more
wiley   +1 more source

Proof-of-concept study: APOE4 brain endothelial cells as a phenotypic compound screen. [PDF]

Alzheimers Res Ther
Valencia-Olvera AC, Marottoli FM, Ratia K, Thatcher GR, Tai LM.   +4 more
europepmc   +1 more source

Characterization of an Injectable Poly(vinyl alcohol)‐gelatin Hydrogel for Growth Factor Delivery in an Orthopedic Application

Advanced Healthcare Materials, EarlyView.
This work introduces photo‐crosslinkable tyraminated poly(vinyl alcohol)‐gelatin (PVA‐GT) hydrogels as tunable injectable platforms for tissue engineering and growth factor delivery applications. This schematic illustrates the two developed hydrogel formulations and the experimental workflow used to evaluate their physico‐chemical properties in vitro ...
Alessia Longoni, Gretel S. Major, Sam Arnold, Samuel Tomkins, Eugenia Spessot, Scott Loeffler, Kieran Lau, Richard Tan, Jessica Harte, Roslyn Kemp, Tess Reynolds, Jelena Rnjak‐Kovacina, Gary J. Hooper, Tim B. F. Woodfield, David C. Kieser, Khoon S. Lim   +15 more
wiley   +1 more source

Musical harmony is processed during sleep: a proof-of-concept study. [PDF]

Sleep Adv
Wick AZ, Rasch B.
europepmc   +1 more source

Advanced 3D Platforms for Modeling CNS Neuroinflammation: Cell Integration, Techniques, and Challenges

Advanced Healthcare Materials, EarlyView.
This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi, Julia Di Stefano, Dearbhaile Dooley   +2 more
wiley   +1 more source

Non-invasive cardiac power measurements in decompensated heart failure in elderly adults: A prospective proof-of-concept study. [PDF]

Physiol Rep
Yttervoll I, Østvik A, Aadahl P, Mo R, Grenne B, Kirkeby-Garstad I.   +5 more
europepmc   +1 more source