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Proof-of-Concept Studies for Psychosocial Interventions
Abstract This chapter explains the purpose of proof-of-concept study and describes the methods used to determine whether an intervention has impacted a hypothesized target. Proof-of-concept trials are the initial step in the clinical trial pipeline and are needed before more investment is made in larger pilot and efficacy trials. ThisPatricia A. Areán, Michael D. Pullmann
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Analgesic drug development: proof-of-mechanism and proof-of-concept in early phase clinical studies
Medicine in Drug Discovery, 2021Geert Jan Groeneveld
exaly
Efficient two-stage sequential arrays of proof of concept studies for pharmaceutical portfolios
Statistical Methods in Medical Research, 2021Linchen He +2 more
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Privacy-preserving local analysis of digital trace data: A proof-of-concept
Patterns, 2022Laura Boeschoten +2 more
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CT-based emphysema characterization per lobe: A proof of concept
European Journal of Radiology, 2023Hendrik Joost Wisselink +2 more
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