Results 51 to 60 of about 204,238 (306)

Diamond turning of soft semiconductors to obtain nanometric mirror surfaces [PDF]

, 2002
Diamond cutting is a viable alternative to grinding and polishing in the fabrication of high-quality soft semiconductors. Investigation of indentation provides useful information for understanding the practical diamond cutting process of brittle ...
Fang, Fengzhou Z., Venkatesh, Vasisht,C., Zhang, G.X.   +2 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Optimization of planting materials for large scale plantation of Bambusa balcooa Roxb.: Influence of propagation methods

Journal of the Saudi Society of Agricultural Sciences, 2018
One of the key insufficiencies of the reports on in vitro propagation of tree species is that the field performances of the in vitro regenerants are not reported in majority of the studies.
Saikat Gantait, Binay Ray Pramanik, Maitreyi Banerjee   +2 more
doaj   +1 more source

Apparatus for monitoring linear explosive performance [PDF]

, 1974
Techniques provide performance monitoring standard for acceptance, lot qualification, and comparison testing of devices. Exhibit high degree of simplicity, accuracy, and reproducibility.
Bement, L. J.
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Prediction and Analysis of the Surface Roughness in CNC End Milling Using Neural Networks

Applied Sciences, 2021
In the metal cutting process of machine tools, the quality of the surface roughness of the product is very important to improve the friction performance, corrosion resistance, and aesthetics of the product.
Cheng-Hung Chen, Shiou-Yun Jeng, Cheng-Jian Lin   +2 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Mesoscopic Damage Simulation of Sandstone during PDC-Cutter Cutting

Shiyou jixie, 2023
In the process of rock cutting,the cutting parameters of the tool have important influences on the failure mode and rock-breaking efficiency.In order to investigate the mesoscopic damage of sandstone cut by PDC cutter under different cutting parameters ...
Yang Hongyu, Deng Rong, Ye Bailiang, He Xiangjiang, Huang Anlong   +4 more
doaj  

Micropropagation of Duboisia Species: A Review on Current Status

Agronomy, 2023
Duboisia is an Australian native woody species of the Solanaceae family, a crucial source of alkaloids, and is naturally extracted for pharmaceuticals. The alkaloid content of the four naturally occurring species of Duboisia, i.e., Duboisia myoporoides R.
Yuxin Xue, Jayeni Chathurika Amarathunga Hiti-Bandaralage, Neena Mitter   +2 more
doaj   +1 more source