Results 31 to 40 of about 68,121 (257)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
This paper mainly investigates the application of underwater acoustic sensor networks (UASNs), which are characterized by large-scale, sparse distribution, and varying traffic loads.
Xiaoxiao Zhuo +5 more
doaj +1 more source
A Theoretical Modeling of Adaptive Mixed CNT Bundles for High-Speed VLSI Interconnect Design
The aroused quest to reduce the delay at the interconnect level is the main urge of this paper, so as to come across a configuration of carbon nanotube (CNT) bundles, namely, squarely packed bundles of mixed CNTs.
Abu Bony Amin +2 more
doaj +1 more source
Modeling plant virus propagation with delays
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Mark Jackson, Benito M. Chen-Charpentier
openaire +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Recovering the propagation delay of an optical pulse
Causality and special relativity pose an upper limit to the amount of advance that an optical pulse can acquire during a superluminal propagation. Such a limit can be circumvented if the pulse, before entering the superluminal medium, is retarded by letting it propagate under normal dispersion.
TOMMASI, FEDERICO +3 more
openaire +4 more sources
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
Vedic division methodology for high-speed very large scale integration applications
Transistor level implementation of division methodology using ancient Vedic mathematics is reported in this Letter. The potentiality of the ‘Dhvajanka (on top of the flag)’ formula was adopted from Vedic mathematics to implement such type of divider for ...
Prabir Saha +3 more
doaj +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source

