Results 31 to 40 of about 68,121 (257)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Delay and Queue Aware Adaptive Scheduling- Based MAC Protocol for Underwater Acoustic Sensor Networks

open access: yesIEEE Access, 2019
This paper mainly investigates the application of underwater acoustic sensor networks (UASNs), which are characterized by large-scale, sparse distribution, and varying traffic loads.
Xiaoxiao Zhuo   +5 more
doaj   +1 more source

A Theoretical Modeling of Adaptive Mixed CNT Bundles for High-Speed VLSI Interconnect Design

open access: yesCrystals, 2022
The aroused quest to reduce the delay at the interconnect level is the main urge of this paper, so as to come across a configuration of carbon nanotube (CNT) bundles, namely, squarely packed bundles of mixed CNTs.
Abu Bony Amin   +2 more
doaj   +1 more source

Modeling plant virus propagation with delays

open access: yesJournal of Computational and Applied Mathematics, 2017
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Mark Jackson, Benito M. Chen-Charpentier
openaire   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Recovering the propagation delay of an optical pulse

open access: yesOptics Express, 2014
Causality and special relativity pose an upper limit to the amount of advance that an optical pulse can acquire during a superluminal propagation. Such a limit can be circumvented if the pulse, before entering the superluminal medium, is retarded by letting it propagate under normal dispersion.
TOMMASI, FEDERICO   +3 more
openaire   +4 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Vedic division methodology for high-speed very large scale integration applications

open access: yesThe Journal of Engineering, 2014
Transistor level implementation of division methodology using ancient Vedic mathematics is reported in this Letter. The potentiality of the ‘Dhvajanka (on top of the flag)’ formula was adopted from Vedic mathematics to implement such type of divider for ...
Prabir Saha   +3 more
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

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