Results 121 to 130 of about 1,632,333 (335)

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento   +3 more
wiley   +1 more source

Cohesive zone modeling of creep–fatigue crack propagation with dwell time

open access: yesAdvances in Mechanical Engineering, 2017
In engineering application, a quantitative description of both fatigue and creep damage mechanisms is demanded for high-temperature alloy. This work employs the cohesive zone model to numerically simulate the crack propagation in a nickel-based super ...
Wen Li   +3 more
doaj   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng   +4 more
wiley   +1 more source

Spatiotemporal dynamic characteristics and influencing factors of propagation time from meteorological drought to agricultural drought

open access: yesJournal of Hydrology: Regional Studies
Study region: Yangtze River Basin (YRB), China Study focus: Understanding the propagation from meteorological to agricultural drought is essential for effective agricultural drought risk management.
Zhengguang Xu   +3 more
doaj   +1 more source

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub   +24 more
wiley   +1 more source

Comprehensive Assessment of Arterial, Tissue, and Venous Collaterals for Evaluating the Infarct Growth Rate: The Multimodal Collateral Score

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto   +12 more
wiley   +1 more source

Comparison of FDTD and TDWP Methods for Simulating Electromagnetic Wave Propagation above Terrains

open access: yesJournal of Microwaves, Optoelectronics and Electromagnetic Applications
Researchers have always been in face of path loss calculation in different media for applications such as telecommunication link design. Wave propagation calculations in large spaces using the FDTD method is time-consuming and imposes a great ...
Mahmoud Fallah, Amir. H Nazeri
doaj   +1 more source

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