Results 251 to 260 of about 24,794 (297)

Mechanistic Foundations of KRAS‐Driven Tumor Ecosystems: Integrating Crosstalk among Immune, Metabolic, Microbial, and Stromal Microenvironment

Advanced Science, EarlyView.
KRAS mutations dynamically remodel the tumor microenvironment (TME), fostering immunosuppression, metabolic symbiosis, and stromal plasticity. This review dissects how oncogenic KRAS variants sculpt TME networks and explores actionable vulnerabilities. Emerging strategies combining KRAS inhibitors and TME‐editing approaches offer potential to dismantle
Jiayao Ma, Shenao Fu, Jun Tan, Ying Han, Yihong Chen, Xiangying Deng, Hong Shen, Shan Zeng, Yinghui Peng, Changjing Cai   +9 more
wiley   +1 more source

The Need to Emphasize Inhaler Education in Residency and Fellowship Training in the Era of Climate Change. [PDF]

J Grad Med Educ
Yeo A, Lui JK.
europepmc   +1 more source

Living Biotherapeutics Using Nanoparticles‐Armed Cyanobacteria for Boosting Photodynamic‐Immunotherapy of Cancer

Advanced Science, EarlyView.
A schematic illustration of the cyanobacteria‐based biohybrid platform for photodynamic cancer therapy enhanced PDT. The platform continuously outputs O2 (to alleviate tumor hypoxia) and 1O2 (for tumor treatment), achieving improved photodynamic immunotherapy. Abstract The interdisciplinary development of synthetic biology and material sciences propels
Zhengwei Xu, Mingsong Zang, Hui Li, Ruizhen Tian, Zherui Zhang, Wang Liu, Fei Xiao, Xuesha Yan, Yan Zhu, Canhong Zhu, Jiayun Xu, Shuangjiang Yu, Tingting Wang, Hongcheng Sun, Junqiu Liu   +14 more
wiley   +1 more source

Use of metered dose inhalers for bronchodilator responsiveness testing: laboratory practices in Australia and opportunities for carbon footprint reduction. [PDF]

BMJ Open Respir Res
Loftus MJ, Roberts J, Romeo N, Matsas P, Leder K, Borg B, Miller BR.   +6 more
europepmc   +1 more source

Self‐Propelled In Situ Polymerized Nanoparticles Activating the STING Pathway for Enhanced Bladder Cancer Immunotherapy

Advanced Science, EarlyView.
A self‐propelled nanomedicine delivery system forms DMCU nanoparticles in the bladder via in situ polymerization of dopamine hydrochloride, Mn2+, cGAMP, and urease. The urease‐driven propulsion enhances retention and drug delivery. These nanoparticles activate the STING pathway, stimulating dendritic cells and T cells to boost anti‐bladder cancer ...
Lei Peng, Anguo Zhao, Rongkang Li, Yujun Liu, Daitian Tang, Dashi Deng, Qi Zhuang, Rui Liang, Shaohua Zhang, Song Wu   +9 more
wiley   +1 more source

Environmental impact of inhaled medicines: A Thoracic Society of Australia and New Zealand position statement. [PDF]

Respirology
Wurzel DF, Montgomery BD, Anderson N, Schneider-Futschik EK, George J, Bosnic-Anticevich S, Stone E, Hancox RJ, Fingleton J, Kuek S, Tope H, Blakey J.   +11 more
europepmc   +1 more source

In Situ Assembly of Fluorogenic RNA for Screening Natural Anti‐Liver Fibrosis Products via Dynamic Visualization of COL1A1 mRNA

Advanced Science, EarlyView.
This study introduces an in situ assembly of fluorogenic RNA approach for screening natural anti‐liver fibrosis compounds and dynamic visualization of endogenous COL1A1 mRNA in live cells. It offers a simple, cost‐effective approach of visualizing RNA dynamics and conducting drug screening in live cells, presenting a significant potential for the ...
Rui Bai, Li‐Zeng Zhu, Changfa Shao, Zheng Yin, Qun Liu, Yu Gu, Bin Liu   +6 more
wiley   +1 more source

Inhaler Recycling: Environmental Impact and Patient Participation. [PDF]

Open Respir Arch
Díez Piña JM, Martínez Núñez R, Vázquez Domínguez J, Reyes Núñez N, Montero Sanz P, Vera Pila A, Mascarell Roda T.   +6 more
europepmc   +1 more source

A Soft‐Soft Contact Triboelectric Nanogenerator with a Ternary Four‐Phase Structure for Self‐Powered High‐Efficiency Dust Removal on Mars

Advanced Science, EarlyView.
The frequent dust storms and charged dust particles on Mars pose significant challenges to the power generation efficiency and service life of solar panels during exploration missions. This paper proposes a novel wind‐driven ternary four‐phase soft‐soft contact triboelectric nanogenerator (FPS‐TENG) for dust removal.
Fei Yang, Zheping Wang, Boyi Xu, Yifan Lu, Xuyan Hou, Jinsui Xu, Zhijie Xie   +6 more
wiley   +1 more source

Effect of aluminum and ammonium perchlorate particle sizes on the condensed combustion products characteristics of aluminized NEPE propellants. [PDF]

Sci Rep
Tu C, Chen X, Chen F, Zhuang Y, Cai W, Li Y, Li W, Zhou C, Xie R.   +8 more
europepmc   +1 more source