Results 261 to 270 of about 84,409 (357)

Microglia‐Targeted Biomimetic Tetrahedral Framework Nucleic Acid Nanovesicles for Synergistic Treatment of Sepsis‐Associated Encephalopathy

open access: yesAdvanced Science, EarlyView.
Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi   +15 more
wiley   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

open access: yesAdvanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao   +3 more
wiley   +1 more source

Radiation‐Resistant Kr‐Selective MOF With Record Kr/Xe Selectivity at Elevated Pressure

open access: yesAdvanced Science, EarlyView.
ABSTRACT The separation of Kr/Xe from spent nuclear fuel off‐gas is critical, yet most current adsorbents exhibit Xe‐Kr co‐adsorption under elevated pressures, posing challenges for industrial pressure swing adsorption processes. Herein, we present and evaluate a metal‐organic framework, CALF‐20M‐w, engineered for molecular sieving separation of Kr/Xe ...
Qihang Tian   +6 more
wiley   +1 more source

Light‑Driven Propulsion of Graphene Aerogels in Microgravity

open access: yesAdvanced Science, EarlyView.
Ultralight graphene aerogels convert laser light into thrust. Parabolic‐flight experiments directly compare their motion in microgravity and at 1 g, revealing order‐of‐magnitude enhancements in distance, velocity, and transient thrust when weight and friction are removed (∼50 times enhancement).
Omnia Khattab   +10 more
wiley   +1 more source

Bioinspired Morphology‐Decoupled Soft Gripper with Enhanced Bidirectional Grasping Capability

open access: yesAdvanced Science, EarlyView.
Inspired by biological predation, a novel gripper decouples cross‐modal grasping via dual morphological configurations. Synergistically integrating hybrid rigid and soft coupled fingers with a metamaterial palm, the system performs active compliant grasping for static objects and passive cage capture for dynamic targets.
Yedong Huang   +4 more
wiley   +1 more source

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