Results 131 to 140 of about 3,722,033 (368)

Employment Effects of Service Offshoring: Evidence from Matched Firms [PDF]

open access: yes
This paper studies the e¤ects of service o¤shoring on the level and skill composition of domestic employment, using a rich data set of Italian rms and propensity score matching techniques.
Rosario Crinò
core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

The specification of the propensity score in multilevel observational studies [PDF]

open access: yes
Propensity Score Matching (PSM) has become a popular approach to estimation of causal effects. It relies on the assumption that selection into a treatment can be explained purely in terms of observable characteristics (the “unconfoundedness assumption ...
Arpino, Bruno, Mealli, Fabrizia
core   +1 more source

Corticosteroid Therapy for Patients with Severe Fever with Thrombocytopenia Syndrome: A Nationwide Propensity Score-Matched Study in Japan

open access: green, 2023
Hisayuki Shuto   +6 more
openalex   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Can nutritional label use influence body weight outcomes? [PDF]

open access: yes
Nutritional labeling has been of much interest to policy makers and health advocates due to rising obesity trends. So can nutritional label use really help reduce body weight outcomes?
Andreas Drichoutis   +2 more
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Impact of SGLT2 Inhibitors on Very Elderly Population with Heart Failure with Reduce Ejection Fraction: Real Life Data

open access: yesBiomedicines
(1) Background: The validation of new lines of therapy for the elderly is required due to the progressive ageing of the world population and scarce evidence in elderly patients with HF with reduced ejection fraction (HFrEF).
Jorge Balaguer Germán   +9 more
doaj   +1 more source

“Clinical Stability” and Propensity Score Matching in Cardiac Surgery: is the clinical evaluation of treatment efficacy algorithmdependent in small sample size settings?

open access: yesEpidemiology, Biostatistics and Public Health, 2022
Background: Propensity score matching represents one of the most popular techniques to deal with treatment allocation bias in observational studies. However, when the number of enrolled patients is very low, the creation of matched set of subjects may
Daniele Bottigliengo   +21 more
doaj  

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