Results 71 to 80 of about 202,432 (260)

Soil resilience mapping in selective wetlands, West Suez Canal, Egypt

Egyptian Journal of Remote Sensing and Space Sciences, 2011
The aims of this study are: (1) producing a geometrically corrected physiographic-soil map scale 1:50,000 reduced to the attached map; (2) detecting some soil characteristics as (effective soil depth, salinity and alkalinity) of the investigated area ...
W.A. Abdel Kawy, Abdel-Aziz Belal
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Communication in Chronic Disease Care: A Collaborative Conversation Map

Journal of the Pakistan Medical Association
Chronic diseases require long term commitment from both the patient and the treating physician for improving their clinical outcomes. This journey can be made more easier if a proper communication bridge can be made between both of them.
Sanjay Kalra, Saurabh Arora, Nitin Kapoor   +2 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Proposal for processes map of post-consumption reverse logistics under the perspective of the national solid waste policy

GEPROS: Gestão da Produção, Operações e Sistemas, 2017
The National Policy on Solid Waste (NPSW) points to the Reverse Logistics (RL) as an instrument that enables actions and strategies that allow adequate management of Urban Solid Waste (USW) according to their guidelines.
Emmily Caroline Cabral da Fonseca, Eriton Carlos Martins Barreiros, Paulo Vitor dos Santos Gonçalves, André Cristiano Silva Melo, Denilson Ricardo de Lucena Nunes   +4 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Dimension of the set of positive solutions to nonlinear equations and applications

Electronic Journal of Differential Equations, 2016
We study the covering dimension of the set of (positive) solutions to various classes of nonlinear equations involving condensing and A-proper maps. It is based on the nontriviality of the fixed point index of a certain condensing map or on oddness ...
Petronije S. Milojevic
doaj  

On the completeness of contraction map proof method for holographic entropy inequalities

Journal of High Energy Physics
The contraction map proof method is the commonly used method to prove holographic entropy inequalities. Existence of a contraction map corresponding to a holographic entropy inequality is a sufficient condition for its validity. But is it also necessary?
Ning Bao, Keiichiro Furuya, Joydeep Naskar   +2 more
doaj   +1 more source

Mapa político del mundo: entidades no representadas o representadas inadecuadamente [PDF]

Cinq Continents, 2012
World political map: territories unrepresented or inadequately represented. The political map of the world is probably the most common source of information regarding the reality of the political geography of our planet.
TIMOTEI RAD
doaj  

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source