Results 131 to 140 of about 2,388,514 (295)
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar +11 more
wiley +1 more source
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
What is meaningfull proper name?
The theme of this Thesis can be characterized by one question: "What is the meaningful proper name?" The tradition of analytical philosophy is the departure point for finding the answer.
Volák, Martin
core
Proper name anomia after right-hemispheric lesion: A case study
Geukes C, Müller HM. Proper name anomia after right-hemispheric lesion: A case study. Neurocase. 2015;21(4):520-528.This study describes the case of CH, a 68-year-old left-handed woman who suffered a right temporo-parieto-occipital infarct in the ...
Geukes, Cornelia +1 more
core +1 more source
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source
Neurolinguistic approaches to proper name processing
Müller HM. Neurolinguistic approaches to proper name processing. In: Proceedings of the 22nd International Congress of Onomastic Science Pisa Italy, p.
Müller, Horst M. ; https://orcid.org/
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Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada +7 more
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Neurolinguistic approaches to proper name processing
Müller HM. Neurolinguistic approaches to proper name processing. In: Arcamone MG, ed. Proceedings of the 22. International Congress of Onomastic Sciences.
Arcamone, M.G. +1 more
core
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source

