The Genetic Origin of Uneven Cognitive Profiles in Heritable Neurodevelopmental Conditions and Individual Differences: Computational Investigations. [PDF]
Dev SciKohli M, Magoulas G, Thomas MSC.
europepmc +1 more source
FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Next-Generation PVA-Dye Complex Film with Advanced Properties for Optical Applications. [PDF]
Polymers (Basel)Ma R, Yu Y.
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Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
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Influence of the Fibrous Network Architecture on the Mechanical Properties of Melt-Blown Non-Woven Thermoplastic Polyurethane Fabrics. [PDF]
Polymers (Basel)Wang Q +5 more
europepmc +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Theoretical Considerations for Patient-Specific Modeling Based on Observable State Variables. [PDF]
J Biomech EngAteshian GA, Deiters S, Weiss JA.
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FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
Mechanistic modulation of electronic structure and interface chemistry in Ni-based alloys for electrochemical energy conversion. [PDF]
RSC AdvAli Umar A, Oyama M.
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