Results 241 to 250 of about 8,707,734 (384)

DrugDiff: small molecule diffusion model with flexible guidance towards molecular properties. [PDF]

J Cheminform
Oestreich M, Merdivan E, Lee M, Schultze JL, Piraud M, Becker M.   +5 more
europepmc   +1 more source

A potential tumor suppressor role of PLK2 in glioblastoma

FEBS Open Bio, EarlyView.
PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia, Peirui Wang, Hua Xiao, Qishan Ran, Yan Li, Shengtao Yao   +5 more
wiley   +1 more source

Accurately adjusted phenothiazine conformations: reversible conformation transformation at room temperature and self-recoverable stimuli-responsive phosphorescence. [PDF]

Light Sci Appl
Gao Y, Yuan W, Li Y, Huang A, Fang Y, Li A, Wang K, Zou B, Li Q, Li Z.   +9 more
europepmc   +1 more source

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

FEBS Open Bio, EarlyView.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law, Yuan Gao, Sravya Kovvali, Pankajavalli Thirugnanasambantham, Vicki H. Wysocki, Brian M. M. Ahmer, Venkat Gopalan   +6 more
wiley   +1 more source

Relation between the Polarizability of Ions and other Significant Properties [PDF]

, 1959
K. Krishnamurti
openalex   +1 more source

Exploring perspectives of the Unified Patent Court and Unitary Patent within the business and legal communities [PDF]

, 2014
Intellectual Property Office, McDonagh, L.   +1 more
core  

MulAFNet: Integrating Multiple Molecular Representations for Enhanced Property Prediction. [PDF]

ACS Omega
Ci L, Li B, Xu J, Peng S, Jiang L, Long W.   +5 more
europepmc   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

CRYSTALLOGRAPHIC AND OPTIC PROPERTIES OF MANNOKETOHEPTOSE AND OF THE OSAZONES OF MANNOKETOHEPTOSE AND MANNOALDOHEPTOSE

, 1917
F. E. Wright
openalex   +1 more source

Table of Contents [PDF]

, 2005
Buffalo Intellectual Property Law Journal
core   +1 more source