Results 241 to 250 of about 16,754,236 (393)

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

Molecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho, Yubin Hah, Eunsik Yun, Hye In Ka, Aram Lee, Sora Han, Dawn Lee, Sung Wook Kim, Jong Hoon Park, Byung Su Kwon, Young Yang, Jongmin Kim   +11 more
wiley   +1 more source

Application of a Quantitative Real-Time PCR Assay for Early Detection of <i>Salmonella enterica</i> Serovar Enteritidis on Poultry Farms During an Outbreak in New South Wales, Australia (2018-2020). [PDF]

Transbound Emerg Dis
Onizawa E, Westman ME, Bogema DR, Deutscher AT, Eamens K, Micallef ML, McDonogh T, Jenkins C.   +7 more
europepmc   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

Fabric Tactile Prediction Method Based on Spider Diagram. [PDF]

Sensors (Basel)
Xie R, Ding S, Cheng Z, Ma L, Yang Y.
europepmc   +1 more source

Catalogue of plants in the two metropolitan gardens, the Brisbane Botanic Garden and Bowen Park : (The garden of the Queensland Acclimatisation Society) arranged according to Bentham and Hooker's "Genera Plantarum", interspersed with numerous notes on the uses and properties of the plants

, 1885
Frederick Manson Bailey
openalex   +2 more sources

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

From archives to AI: Residential property data across three decades in Brunei Darussalam. [PDF]

Data Brief
Jamil H, Noorosmawie AB, Rabu HW, Abdul Razak L.   +3 more
europepmc   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

A knowledge-based clinical decision support system for personalized health examination items in China: design and evaluation. [PDF]

BMC Med Inform Decis Mak
Wu D, An J, Nan S, She Y, Duan H, Deng N.   +5 more
europepmc   +1 more source

Property testing and its connection to learning and approximation

Proceedings of 37th Conference on Foundations of Computer Science, 1996
Oded Goldreich, S. Goldwasser, D. Ron
semanticscholar   +1 more source