Results 71 to 80 of about 1,341,547 (266)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
A Lithuanian “Ethnographic Village”: Heritage, Private Property, Entitlement
In this article, various aspects of engagement with the past and with heritage are explored in the context of Grybija village in southern Lithuania.
Kristina Jonutyte
doaj
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The Reznichenko property and the Pytkeev property in hyperspaces [PDF]
8 ...
openaire +3 more sources
A Memory Advantage for Property
People's access to resources depends on their status as the owner of particular items. To respect property, people need to remember who owns which objects.
Peter DeScioli +2 more
doaj +1 more source
Relations between Shadowing and Inverse Shadowing in Dynamical Systems
In this paper, we study relations between shadowing and inverse shadowing for homeomorphisms of a compact space. We present an example of a smooth diffeomorphism of a compact three-dimensional manifold that has the shadowing property and does not have ...
Alexey A. Petrov
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
A topological property of β(N)
In this paper we prove that the Stone-Cech-compactification of the natural numbers does not admit a countable infinite decomposition into subsets homeomorphic to each other and to the said compactification.
Anastase Nakassis
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

