Results 71 to 80 of about 1,341,547 (266)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

A Lithuanian “Ethnographic Village”: Heritage, Private Property, Entitlement

open access: yesAnthropological Researches and Studies, 2015
In this article, various aspects of engagement with the past and with heritage are explored in the context of Grybija village in southern Lithuania.
Kristina Jonutyte
doaj  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A Memory Advantage for Property

open access: yesEvolutionary Psychology, 2015
People's access to resources depends on their status as the owner of particular items. To respect property, people need to remember who owns which objects.
Peter DeScioli   +2 more
doaj   +1 more source

Relations between Shadowing and Inverse Shadowing in Dynamical Systems

open access: yesAxioms, 2019
In this paper, we study relations between shadowing and inverse shadowing for homeomorphisms of a compact space. We present an example of a smooth diffeomorphism of a compact three-dimensional manifold that has the shadowing property and does not have ...
Alexey A. Petrov
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A topological property of β(N)

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1980
In this paper we prove that the Stone-Cech-compactification of the natural numbers does not admit a countable infinite decomposition into subsets homeomorphic to each other and to the said compactification.
Anastase Nakassis
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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