Results 101 to 110 of about 3,463,553 (284)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Konflik Tanpa Henti: Permukiman dalam Kawasan Taman Nasional Halimun Salak

open access: yesJurnal Manajemen Hutan Tropika, 2011
Conflicts between government and local peoples over national park resources have been occurring in Indonesia, for instance in the Halimun-Salak Mountain National Park (TNGHS).  The research were directed to describe the opinion, relationship, access, and
Sapto Aji Prabowo   +2 more
doaj  

Property Right, Regulation and Economic Growth [PDF]

open access: yesفصلنامه پژوهش‌های اقتصادی ایران, 2010
This paper investigates the role of property right and regulation in credit, business and labor markets on economic growth by using two panel data models for 80 countries during 2000-2005.
Majid Sameti   +2 more
doaj  

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Development of methodological approaches to the accounting of ownership of land assets in Ukraine

open access: yesVìsnik Žitomirsʹkogo Deržavnogo Tehnologìčnogo Unìversitetu: Ekonomìčnì Nauki, 2015
Accounting and legal display of land resources is very important in modern society as the land assets are of great value both for the state as a whole and for each landowner and land user.
T.P. Ostapchuk
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

AVRUPA İNSAN HAKLARI MAHKEMESİ VE ANAYASA MAHKEMESİ KARARLARI IŞIĞINDA BİR ANALİZ: KAMULAŞTIRMA BEDELİNİN TESPİTİ

open access: yesTürk-Alman Üniversitesi Hukuk Fakültesi Dergisi, 2020
Avrupa İnsan Hakları Sözleşmesi (“AİHS”) 1 No’lu Ek Protokol m. 1 ve Türkiye Cumhuriyeti Anayasası (“Anayasa”) m. 35 ile m. 46 kapsamında ele alınmakta olan kamulaştırma müessesesi, çalışmamız kapsamında bedel tespiti boyutuyla ele alınmaktadır.
Didem Bı̇rbı̇r
doaj  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy