Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
The underexplored effects of economic transition on intellectual property rights protection: An economic geography perspective. [PDF]
Gao X +5 more
europepmc +1 more source
Towards vaccine equity: Should big pharma waive intellectual property rights for COVID-19 vaccines? [PDF]
Okereke M.
europepmc +1 more source
Molecular determinants of signal transduction in tropomyosin receptor kinases
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Catherine Boone, Property and Political Order in Africa. Land Rights and the Structure of Politics [PDF]
Jean-Pierre Jacob
openalex +1 more source
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
Intellectual Property, Competition and Human Rights: the past, the present and the future
Abbe Brown and Charlotte Waelde
doaj +1 more source
Sub-sector, property rights system, and performance of China's tourism enterprises: DEA and Luenberger approach. [PDF]
Yang L, Zhu N, Bai H.
europepmc +1 more source
Intellectual Property Rights and Advance Purchase Agreements in a Crisis
Slade A, Hawkins N.
europepmc +1 more source
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani +7 more
wiley +1 more source

