Results 41 to 50 of about 115,242 (266)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Intellectual Property Protection for Graphical User Interfaces [PDF]

open access: yesپژوهشهای حقوقی
A graphical user interface is a fundamental part of any software application as it enables users to interact with an application’s functionality, allowing interaction between computer software and hardware.
Mohammad Mahdi Kateb Damghani   +1 more
doaj   +1 more source

Land use regulation and property rights regime over land in Serbia [PDF]

open access: yesSpatium, 2014
Starting from the fact that land use regulations can directly affect assignment and reassignment of property rights over land, the authors examine the link between land use regulation and property rights in Serbia by analyzing relevant ...
Živanović-Miljković Jelena   +1 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Spatial relationships between farmlands and hydrographies in agrarian landscapes

open access: yesAfrican Journal on Land Policy and Geospatial Sciences
Context and background Climate induced disasters, human involvement, and changes in natural cycles have all had a profound, complex, and difficult-to-understand impact on rural landscapes, especially agrarian landscapes. Most of these negative impacts
Marcel Loyd MINKA
doaj   +1 more source

Justification and System Arrangement of Virtual Property Rights — Comments on Article No. 127 of General Provisions of the Civil Law

open access: yesContemporary Social Sciences, 2019
In the process of formulating the General Provisions of the Civil Law of P. R. China, the attribute of virtual property rights has changed from real rights to non-real rights. Article No. 127 thereof does not clarify the nature of virtual property rights
Li Yan, Ge Hongquan
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Enhancing the adaptive capacities of agrarian landscapes through participatory sketch mapping and spatial perceptions on landmark’s distribution and disparities

open access: yesAfrican Journal on Land Policy and Geospatial Sciences
Agrarian Landscapes are the natural basis for the survival and development of people in rural communities. Participatory sketch mapping refers to the collection of data (spatial, land use and land rights data) through the hand map drawing of study areas
Marcel Loyd MINKA
doaj   +1 more source

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