Results 41 to 50 of about 12,475,597 (335)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Non-Institutional Factors That Contribute to the Green Building Premium

open access: yesLand
This study examines the non-institutional factors that affect the green building premium (GBP). Residential properties are chosen for empirical analysis since they are free from institutional factors such as corporate social responsibility (CSR).
Kwong Wing Chau   +2 more
doaj   +1 more source

Rents in property rights creation and implementation [PDF]

open access: yesEkonomski Anali, 2006
The institution of property rights is increasingly being recognized as an essential building block of an economically prosperous society. The question that remains unanswered however, is how do we develop effective property rights institutions?
Žarković Jelena
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Property rights play a pivotal role in the distribution of ecosystem services among beneficiaries

open access: yesEcosystems and People, 2022
Property rights are fundamental institutions that set the rules for who is allowed to use, manage, and control natural resources. Though the literature on property rights over natural resources is well developed. However, our understanding of the ways by
Marie C. Dade   +2 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Kowloon Walled City: A Case of Land Administration of a Disputed Territory

open access: yesLand
Informed by hitherto unreported archival materials and the relevant literature, this short paper employs a case study of the post-war Hong Kong Government’s administration of the so-called Kowloon Walled City to elucidate two fundamental principles of ...
Lawrence W. C. Lai
doaj   +1 more source

Commodifying the ‘Information Age’: Intellectual Property Rights, the State and the Internet

open access: yesSCRIPTed: A Journal of Law, Technology & Society, 2004
This article examines the role of the state and the rule of law in relation to the problem of intellectual property on the Internet. It concludes that the claim that states are no longer effective actors (and hence subjecting to them to political ...
Christopher May
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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