Results 271 to 280 of about 17,877 (340)

Spatially resolved mapping of histones reveals selective neuronal response in Rett syndrome

The FEBS Journal, EarlyView.
Loss of Mecp2 function is associated with Rett syndrome (RTT). MeCP2 regulates chromatin, yet its influence on histone composition and dynamics is unclear. Combining MALDI‐MSI with LCM–LC–MS/MS, we mapped histone proteoforms across the dentate gyrus, cornu ammonis, and cerebellum in two mouse models of RTT.
Frederike Schäfer, Guiseppa de Rocco, Moritz Völker‐Albert, Ignasi Forne, Nicoletta Landsberger, Axel Imhof, Shibojyoti Lahiri   +6 more
wiley   +1 more source

Unraveling the active site cover of coproheme decarboxylase from Listeria monocytogenes

The FEBS Journal, EarlyView.
During heme biosynthesis in Gram‐positive bacteria, coproheme decarboxylase (ChdC) catalyzes the conversion of four‐propionate substrate coproheme to the two propionate product heme b. Its active site is universally covered by a flexible linking loop. This study identifies an important histidine residue, which stabilizes the loop in a ChdC homolog.
Nikolaus Falb, Dominik Hörtnagel, Chris Oostenbrink, Paul G. Furtmüller, Stefan Hofbauer   +4 more
wiley   +1 more source

Propionate attenuates osteoarthritis progression by regulating the gut-joint axis. [PDF]

Front Immunol
Han S, Cho KH, Na HS, Jhun J, Moon YM, Choi JW, Kim SJ, Cho ML.   +7 more
europepmc   +1 more source

Clinical and economic outcomes for patients initiating fluticasone propionate/salmeterol combination therapy (250/50 mcg) versus anticholinergics in a comorbid COPD/depression population

, 2012
Dalal AA, Manan Shah, D amp Souza AO, Sameer Chaudhari, Glenn Crater   +4 more
openalex   +1 more source

Genetic Parameters of Methane Emission, Feed Efficiency, Feeding Behaviour, and Growth Traits in Beef Cattle

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT Climate change has intensified the need to reduce greenhouse gas emissions, particularly methane (CH4) from enteric fermentation. Genetic selection has emerged as a promising mitigation strategy; however, studies on Bos taurus indicus , especially Nellore cattle, remain limited.
J. A. Silva, J. P. S. Valente, L. F. M. Mota, G. R. D. Rodrigues, T. L. S. Soares, J. O. S. Marcatto, A. M. Pelaez, F. M. Monteiro, R. C. Canesin, L. G. Albuquerque, M. E. Z. Mercadante   +10 more
wiley   +1 more source

Indole-3-propionic acid supplementation during in vitro maturation improves in vitro production of porcine embryos. [PDF]

BMC Vet Res
Nakayama Y, Otoi T, Zhao N, Nguyen ST, Torigoe N, Lin Q, Bin L, Widodo OS, Tharasanit T, Chatdarong K, Hirata M, Nagahara M, Tanihara F.   +12 more
europepmc   +1 more source

Leukemia cutis as the first manifestation of acute myeloid leukemia

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Florian Winkler, Rosa Brand, Dino Mehic, Felix Tuchmann, Teresa Valero, Johanna Strobl   +5 more
wiley   +1 more source

Altered conformational dynamics contribute to species-specific effects of cytochrome c mutations on caspase activation. [PDF]

J Biol Inorg Chem
Chin TC, Wilbanks SM, Ledgerwood EC.
europepmc   +1 more source

Artemisinin attenuates 3-nitropropionic acid-induced neurodegeneration via HMGB1/TLR4/NF-κB modulation in a rat model of huntington's disease. [PDF]

Arch Pharm Res
Mustafa AM, Mudhafar M, Elgindy AM, Esmail MM, Atwa AM, Shaheen AM, Radwan AF, Elfar N, Mohamed RYA, Gamil NM.   +9 more
europepmc   +1 more source

Role of gut microbiome in suppression of cancers. [PDF]

Gut Microbes
Xu Y, Gao Z, Liu J, Yang Q, Xu S.
europepmc   +1 more source