Results 301 to 310 of about 149,099 (355)
Cell Death and Disease, 2019 Propofol infusion syndrome (PRIS) is an uncommon life-threatening complication observed most often in patients receiving high-dose propofol. High-dose propofol treatment with a prolonged duration can damage the immune system.
Lingbin Sun +2 more
exaly +2 more sources
Effects of propofol on the development of cancer in humans
Cell Proliferation, 2020 Cancer is one of most the significant threats to human health worldwide, and the primary method of treating solid tumours is surgery. Propofol, one of the most widely used intravenous anaesthetics in surgery, was found to be involved in many cancer ...
Xueqiong Zhu
exaly +2 more sources
Propofol: A Review of its Role in Pediatric Anesthesia and Sedation
CNS Drugs, 2015 Vidya Chidambaran
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2008
The hypnotic agent propofol has pharmacokinetic characteristics that allow for rapid onset and offset of drug effect and fast elimination from the body. Elderly patients show a greater sensitivity to the hypnotic effect of propofol. The drug is extensively metabolized in the liver through the cytochrome P450 system and glucuronidation, with potential ...
Vanlersberghe, C., Camu, Fréderic
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The hypnotic agent propofol has pharmacokinetic characteristics that allow for rapid onset and offset of drug effect and fast elimination from the body. Elderly patients show a greater sensitivity to the hypnotic effect of propofol. The drug is extensively metabolized in the liver through the cytochrome P450 system and glucuronidation, with potential ...
Vanlersberghe, C., Camu, Fréderic
openaire +3 more sources
Propofol and the electroencephalogram
Clinical Neurophysiology, 2010Propofol is an emulsion formulation of 2,6 diisopropylphenol developed in 1975. Widely recognized, it offers beneficial effects compared with other sedative drugs. Propofol is used in several clinical situations including multiple surgical procedures and critical-care medical conditions.
Andrew J. Cole +2 more
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European Journal of Anaesthesiology, 2019
BACKGROUND Endoscopic retrograde cholangiopancreatography (ERCP) is one of the most complex gastrointestinal endoscopic procedures. Currently, it is still unclear which sedation regimen best facilitates an ERCP.
S. Eberl +6 more
semanticscholar +1 more source
BACKGROUND Endoscopic retrograde cholangiopancreatography (ERCP) is one of the most complex gastrointestinal endoscopic procedures. Currently, it is still unclear which sedation regimen best facilitates an ERCP.
S. Eberl +6 more
semanticscholar +1 more source
Journal of Clinical Anesthesia, 1989
A review of the pharmacology of propofol, a new IV anesthetic agent, is presented. Solubilized in a soybean emulsion, propofol is one of a series of sterically hindered phenols that exhibit anesthetic activity. Induction of anesthesia with propofol may be associated with pain on injection, apnea, and a reduction in arterial blood pressure (BP) and ...
Mark A. Skues, Cedric Prys-Roberts
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A review of the pharmacology of propofol, a new IV anesthetic agent, is presented. Solubilized in a soybean emulsion, propofol is one of a series of sterically hindered phenols that exhibit anesthetic activity. Induction of anesthesia with propofol may be associated with pain on injection, apnea, and a reduction in arterial blood pressure (BP) and ...
Mark A. Skues, Cedric Prys-Roberts
openaire +3 more sources
Critical Care Medicine, 2019
Objectives: Propofol-based sedation may increase hemodynamic instability by decreasing vascular tone and venous return. Incremental exogenous catecholamines doses may be required to counteract such effects, aggravating the deleterious effects of ...
A. Morelli +12 more
semanticscholar +1 more source
Objectives: Propofol-based sedation may increase hemodynamic instability by decreasing vascular tone and venous return. Incremental exogenous catecholamines doses may be required to counteract such effects, aggravating the deleterious effects of ...
A. Morelli +12 more
semanticscholar +1 more source
Comparison of Propofol‐Lipuro with propofol mixed with lidocaine 10 mg on propofol injection pain
Anaesthesia, 2004SummaryA common drawback of propofol is pain on injection and lidocaine is commonly mixed with propofol to reduce its incidence and severity. We conducted a randomised, prospective, double‐blind study to compare injection pain following the administration of two different formulations of propofol in 200 unpremedicated ASA I–III adult patients scheduled
A. McCluskey, M. S. Abdul-Latif, E. Kam
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