Results 61 to 70 of about 2,348 (259)

Design of a current controller for symmetrical six‐phase fault‐tolerant PMSM under fault conditions

open access: yesIET Power Electronics, 2022
To achieve the fault‐tolerant operation of motor drives, many control algorithms have been proposed. Among them, it is more flexible and intuitive to find solutions to phase current at phase coordinate.
Yixiao Feng, Yong Liao, Fan Ye
doaj   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

open access: yesFEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Harmonic Suppression in Permanent Magnet Synchronous Motor Currents Based on Quasi-Proportional-Resonant Sliding Mode Control

open access: yesApplied Sciences
The output voltage of inverters is influenced by nonlinear factors such as dead time and voltage drops, injecting low-order harmonics. This results in fifth and seventh harmonic distortions in the stator current, causing periodic torque ripples and ...
Kelu Wu   +4 more
doaj   +1 more source

Lyapunov-Function-Based Controller for Single-Phase NPC Quasi-Z-Source Inverter with 2ω Frequency Ripple Suppression

open access: yesEnergies, 2020
This paper proposes a high-performance control technique based on Lyapunov’s stability theory for a single-phase grid-connected neutral-point-clamped quasi-impedance source inverter with LCL filter.
Sertac Bayhan, Hasan Komurcugil
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

A Single-Loop Repetitive Voltage Controller with an Active Damping Control Technique

open access: yesEnergies, 2017
This paper proposes a single-loop repetitive voltage control strategy which incorporates the active damping control feature for single-phase uninterruptible power supply (UPS) applications.
Younghoon Cho   +3 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

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