A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento +3 more
wiley +1 more source
Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer +11 more
wiley +1 more source
PICBayes: Bayesian proportional hazards models for partly interval-censored data. [PDF]
Pan C, Cai B.
europepmc +1 more source
Comparison between asymptotic and re-randomisation tests under non-proportional hazards in a randomised controlled trial using the minimisation method. [PDF]
Kimura R, Nomura S, Nagashima K, Sato Y.
europepmc +1 more source
Time to treatment-seeking by caretakers of children under-five with diarrhea and associated factors in Uganda: a multilevel proportional hazards analysis. [PDF]
Tumusiime S +5 more
europepmc +1 more source
Absolute risk from double nested case-control designs: cause-specific proportional hazards models with and without augmented estimating equations. [PDF]
Lee M, Gail MH.
europepmc +1 more source
Overall survival with non-proportional hazards in first-line treatment for patients with metastatic colorectal cancer: Systematic review and network meta-analysis. [PDF]
Keshavarzi F +5 more
europepmc +1 more source
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Journal of General Internal Medicine, 1993PROPORTIONAL HAZARDS ( C o x ) REGRESSION is a powerful analytic tool for testing whe the r several factors (e.g., cigarette smoking, hyper tens ion) are independent ly related to the rate (over t ime) of a specific event (e.g., heart attack yes /no) . It can also be used to control for baseline differences be t ween groups in nonrandomized studies and
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