Results 41 to 50 of about 180,194 (260)

A flexible alternative to the Cox proportional hazards model for assessing the prognostic accuracy of hospice patient survival. [PDF]

PLoS ONE, 2012
Prognostic models are often used to estimate the length of patient survival. The Cox proportional hazards model has traditionally been applied to assess the accuracy of prognostic models.
Branko Miladinovic, Ambuj Kumar, Rahul Mhaskar, Sehwan Kim, Ronald Schonwetter, Benjamin Djulbegovic   +5 more
doaj   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Model-based Prediction of Length of Stay for Rehabilitating Stroke Patients

Journal of the Formosan Medical Association, 2009
Accurate length-of-stay (LOS) estimates have an impact on medical costs for stroke patients. Most studies have reported only descriptive sample means or have provided linear-model-based estimates for LOS.
Chien-Lin Lin, Pao-Hsuan Lin, Li-Wei Chou, Shou-Jen Lan, Nai-Hsin Meng, Sui-Foon Lo, Hong-Dar Isaac Wu   +6 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Simulating Survival Data Using the simsurv R Package

Journal of Statistical Software, 2021
The simsurv R package allows users to simulate survival (i.e., time-to-event) data from standard parametric distributions (exponential, Weibull, and Gompertz), two-component mixture distributions, or a user-defined hazard function.
Samuel L. Brilleman, Rory Wolfe, Margarita Moreno-Betancur, Michael J. Crowther   +3 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Advanced Survival Analysis of Iranian Lung Cancer Patients: Prospective Cohort Study of Prognostic Factors [PDF]

علوم بهداشتی ایران
Background and purpose: Addressing survival in lung cancer patients is crucial because it directly informs prognosis, guides personalized treatment strategies, and highlights disparities in healthcare access.
Mahmood Moosazadeh, Ali Asghar Nadi Ghara, Mobina Gheibi, Ghasem Janbabaei, Akbar Hedayatizadeh Omran, Reza Alizadeh-Navaei, Ramin Shekarriz, Ehsan Zaboli, Mohammad Eslami Jouybari, Erfan Ghadirzadeh   +9 more
doaj  

Coach Turnover in Top Professional Brazilian Football Championship: A Multilevel Survival Analysis

Frontiers in Psychology, 2019
In this study, we examined the probability of coaches’ survival in the top Brazilian professional football championship considering variation across the competitive seasons between 2012 and 2017, considering a multilevel framework.
Alexandre B. Tozetto, Alexandre B. Tozetto, Humberto M. Carvalho, Rodolfo S. Rosa, Felipe G. Mendes, Walan R. Silva, Juarez V. Nascimento, Michel Milistetd   +7 more
doaj   +1 more source