Results 41 to 50 of about 191,557 (214)

The impact of violation of the proportional hazards assumption on the discrimination of the Cox proportional hazards model

open access: yesDiagnostic and Prognostic Research
Background The Cox proportional hazards regression model is frequently used to estimate an individual’s probability of experiencing an outcome within a specified prediction horizon. A key assumption of this model is that of proportional hazards.
Peter C. Austin, Daniele Giardiello
doaj   +1 more source

A flexible alternative to the Cox proportional hazards model for assessing the prognostic accuracy of hospice patient survival. [PDF]

open access: yesPLoS ONE, 2012
Prognostic models are often used to estimate the length of patient survival. The Cox proportional hazards model has traditionally been applied to assess the accuracy of prognostic models.
Branko Miladinovic   +5 more
doaj   +1 more source

Early Body Mass Index z‐Score Change and Resolution of Severe Malnutrition in Children With Sickle Cell Anemia in a Low‐Income Setting: A Prospective Single‐Arm Extension Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo   +9 more
wiley   +1 more source

Model-based Prediction of Length of Stay for Rehabilitating Stroke Patients

open access: yesJournal of the Formosan Medical Association, 2009
Accurate length-of-stay (LOS) estimates have an impact on medical costs for stroke patients. Most studies have reported only descriptive sample means or have provided linear-model-based estimates for LOS.
Chien-Lin Lin   +6 more
doaj   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine   +17 more
wiley   +1 more source

Regression Models for Lifetime Data: An Overview

open access: yesStats, 2022
Two methods dominate the regression analysis of time-to-event data: the accelerated failure time model and the proportional hazards model. Broadly speaking, these predominate in reliability modelling and biomedical applications, respectively.
Chrys Caroni
doaj   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani   +7 more
wiley   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin   +17 more
wiley   +1 more source

Advanced Survival Analysis of Iranian Lung Cancer Patients: Prospective Cohort Study of Prognostic Factors [PDF]

open access: yesعلوم بهداشتی ایران
Background and purpose: Addressing survival in lung cancer patients is crucial because it directly informs prognosis, guides personalized treatment strategies, and highlights disparities in healthcare access.
Mahmood Moosazadeh   +9 more
doaj  

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann   +8 more
wiley   +1 more source

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