Results 81 to 90 of about 3,208,441 (315)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

From Plurality Rule to Proportional Representation [PDF]

open access: yes
I consider the decision of a parliament that might change the electoral system for the forthcoming elections from plurality rule to proportional representation. Parties are o¢ ce-motivated. They care about winning and about the share of seats obtained. I
Selim Ergun
core  

Local Favoritism in At-Large Proportional Representation Systems

open access: yesSocial Science Research Network, 2016
Pork barrel spending is typically attributed to the strategic behavior of political elites hoping to be electorally rewarded by voters residing in their districts. Such behavior is expected to depend on the incentives imposed by the electoral system.
Jon H. Fiva, A. Halse
semanticscholar   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Reserve Design under Climate Change: From Land Facets Back to Ecosystem Representation.

open access: yesPLoS ONE, 2015
Ecosystem distributions are expected to shift as a result of global warming, raising concerns about the long-term utility of reserve systems based on coarse-filter ecosystem representation.
Richard R Schneider, Erin M Bayne
doaj   +1 more source

Why not proportional? [PDF]

open access: yes
This paper reviews the arguments that justify the principles of proportional and degressively proportional representation.Proportional representation, Degressive ...
Jean-François Laslier
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

A particular electoral system

open access: yesSfera Politicii, 2019
The parliamentary elections of November 2-9, 1919, were the first collective experience of democracy in the Romanian political space. It was based, after more than five decades of census electoral practice, on the mechanism of universal (male) voting ...
Alexandru Radu
doaj  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

The first elections of the Romanian post‑communism

open access: yesSfera Politicii, 2018
The vote of 20 May 1990 was the one that inaugurated the proportional election of the parliamentarians in the Romanian post-communism, as well as the popular election of the president of the republic.
Alexandru Radu
doaj  

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