Results 41 to 50 of about 353,662 (303)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
The Role of the Double-Layer Potential in Regularised Stokeslet Models of Self-Propulsion
Fluids, 2021 The method of regularised stokeslets is widely used to model microscale biological propulsion. The method is usually implemented with only the single-layer potential, the double-layer potential being neglected, despite this formulation often not being ...
David J. Smith +3 more
doaj +1 more source
, 2011 Marangoni propulsion is a form of locomotion wherein an asymmetric release of surfactant by a body located at the surface of a liquid leads to its directed motion.
Davis, Anthony M. J., Lauga, Eric
core +1 more source
Analysis of Energy Utilization and Losses for Jet-Propelled Vehicles
Aerospace, 2021 The global control volume-based energy utilization balance for an aerospace vehicle is extended to allow for the analysis of jet-propelled vehicles.
Mohammad Abbas, David W. Riggins
doaj +1 more source
Introduction to "To the Question of Energy Use of Detonation Combustion" by Ya. B. Zel'dovich [PDF]
, 2006 Ya. B. Zel’dovich (1914–1987) made numerous contributions [1] to the theory of detonation, beginning with his very well known and widely translated article [2] on detonation structure that first introduced the standard Zel’dovich-von Neumann-Döring (ZND)
Shepherd, J. E., Wintenberger, E.
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak +4 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo +88 more
wiley +1 more source
Advances in Engine Efficiency: Nanomaterials, Surface Engineering, and Quantum-Based Propulsion
MagnetochemistryThis study explores ground-breaking methods for improving engine efficiency by combining cutting-edge materials, theoretical frameworks, and alternative energy paradigms.
Mario J. Pinheiro
doaj +1 more source
Arthritis Care &Research, Accepted Article.Over the past 50 years, the science of pediatric rheumatology has grown exponentially due to an expansion in the understanding of complex rheumatic conditions and a surge in novel targeted therapeutics. Physician‐scientists in the field of pediatric rheumatology have played major roles in these advancements that have improved the care of children ...
Ekemini A. Ogbu +2 more
wiley +1 more source