Results 21 to 30 of about 5,807 (178)

Living with diabetes in the Brazilian Amazon: Exploring barriers and supports for healthy lifestyle practices

open access: yesDiabetic Medicine, EarlyView.
Abstract Aims To investigate the barriers and facilitators to adopting healthy lifestyle habits among patients with type 2 diabetes mellitus (T2DM) in the Brazilian Amazon, using the Environmental Factors domain of the International Classification of Functioning, Disability and Health (ICF) as a conceptual framework.
Thalyta Mariany Rêgo Lopes Ueno   +5 more
wiley   +1 more source

Sobre a possibilidade de se estabelecer um paralelo entre canção e prosa

open access: yesViso, 2019
Objetiva-se com este estudo perscrutar as possibilidades de se estabelecer uma relação entre a canção popular, tal como definida por Luiz Tatit, e a concepção sartriana de prosa como elemento de comunicação, e, portanto, como instrumento político, sem ...
Thiago Rodrigues
doaj   +1 more source

Immuno‐Informatics Design of Multi‐Epitope Vaccine Candidate Against Anaplasma phagocytophilum Using Major Surface Protein 4 (MSP‐4) Antigen

open access: yesHealth Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Bovine anaplasmosis is an intracellular tick‐borne, non‐contagious disease caused by gram‐negative bacteria of the family Anaplasmataceae and order Rickettsia. Anaplasma phagocytophilum is the etiological agent for human granulocytic anaplasmosis associated with severe health implications in parts of Europe and the USA and ...
Samson Anjikwi Malgwi   +5 more
wiley   +1 more source

Zachwaszczenie, plonowanie i efektywność ekonomiczna uprawy prosa zwyczajnego (Panicum miliaceum L.) w zależności od rodzaju herbicydów i ich dawki

open access: yesAgronomy Science, 2022
W artykule przedstawiono wyniki badań prowadzonych w Gospodarstwie Doświadczalnym Czesławice (środkowa Lubelszczyzna, Polska) w latach 2014–2016, dotyczące wpływu wybranych herbicydów nalistnych (2,4-D + fluroksypyr; tribenuron-methyl + fluroksypyr ...
Cezary A. Kwiatkowski   +3 more
doaj   +1 more source

Targeting the noncatalytic activity of GSK3β modulates neuronal excitability in medium spiny neurons via Nav1.6 interactions

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 15, Page 4344-4363, August 2026.
Abstract Background and Purpose Kinases phosphorylate ion channels, but their noncatalytic roles via protein–protein interactions (PPI) are less understood. Here, we identified the peptidomimetic ZL141 to characterize the PPI between GSK3β and Nav1.6, revealing a noncatalytic role for GSK3β in regulating Nav1.6 currents and neuronal excitability ...
Aditya K. Singh   +19 more
wiley   +1 more source

OS SILÊNCIOS POÉTICOS DAS PROSAS: Rousseau por Sartre

open access: yesCadernos de Pesquisa, 2016
Embora Sartre esteja se referindo à figura de vários escritores, e não, especificamente a Rousseau, mas também, a ele, afirma que os poetas são homens que se recusam a utilizar a linguagem, mesmo utilizando-a constantemente.
Luciano da Silva Façanha
doaj   +1 more source

Antologie-cesura: abbiamo davvero varcato quel poi? Dopo la lirica e Prosa in prosa, quindici anni dopo

open access: yesConfigurazioni, 2023
Il contributo indaga la ricezione critica di Dopo la lirica (2005) e Prosa in prosa (2009). Lo fa intervistando il curatore della prima, Enrico Testa, e gli autori, i poeti (auto)antologizzati nel secondo testo, tentando di sgombrare il campo da una ...
Samuele Fioravanti, Anna Stella Poli
doaj   +1 more source

Computational and Experimental Development of a Novel Multi‐Epitope Vaccine Candidate Against Bovine Leukaemia Virus

open access: yesVeterinary Medicine and Science, Volume 12, Issue 4, July 2026.
This study designs a novel multi‐epitope vaccine against bovine leukaemia virus using immunoinformatics. The construct demonstrates high antigenicity, stability, and strong receptor binding, indicating its potential as an effective recombinant vaccine candidate for further experimental validation .
Yasaman Dini   +4 more
wiley   +1 more source

Elucidation of DNA Primase as a Drug Target in Leishmania donovani: Structure‐Guided Inhibitor Identification and Biochemical Validation

open access: yesChemical Biology &Drug Design, Volume 108, Issue 1, July 2026.
Structure‐guided and biochemical analyses indicate that DNA primase of Leishmania donovani represents a potential therapeutic target, as repurposed compounds, particularly Pritelivir, demonstrate marked inhibitory effects accompanied by reduced parasite proliferation, replication, and altered cellular morphology in in vitro and cell‐based studies ...
Deep Bhowmik   +3 more
wiley   +1 more source

Discovery of Potent Antimalarial Agents Targeting Plasmodium falciparum DNA Gyrase B by Integrating Computational and Experimental Approaches

open access: yesChemical Biology &Drug Design, Volume 108, Issue 1, July 2026.
An integrated computational and experimental drug‐discovery approach identified UNC8153 as a potential novel scaffold active against drug‐sensitive and artemisinin‐resistant P. falciparum strains through inhibition of apicoplast PfGyrB. ABSTRACT The global spread of drug‐resistant Plasmodium falciparum, particularly artemisinin‐resistant strains ...
Biswajit Naik   +10 more
wiley   +1 more source

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