Results 21 to 30 of about 923 (101)

Current practice in diagnostic genetic testing of the epilepsies

Epileptic Disorders, Volume 24, Issue 5, Page 765-786, October 2022., 2022
Abstract Epilepsy genetics is a rapidly developing field, in which novel disease‐associated genes, novel mechanisms associated with epilepsy, and precision medicine approaches are continuously being identified. In the past decade, advances in genomic knowledge and analysis platforms have begun to make clinical genetic testing accessible for, in ...
Ilona Krey, Konrad Platzer, Alina Esterhuizen, Samuel F. Berkovic, Ingo Helbig, Michael S. Hildebrand, Holger Lerche, Daniel Lowenstein, Rikke S. Møller, Annapurna Poduri, Lynette Sadleir, Sanjay M. Sisodiya, Sarah Weckhuysen, Jo M. Wilmshurst, Yvonne Weber, Johannes R. Lemke   +15 more
wiley   +1 more source

Natural variation of HTH5 from wild rice, Oryza rufipogon Griff., is involved in conferring high‐temperature tolerance at the heading stage

Plant Biotechnology Journal, Volume 20, Issue 8, Page 1591-1605, August 2022., 2022
Summary Global warming is a major abiotic stress factor, which limit rice production. Exploiting the genetic basis of the natural variation in heat resistance at different reproductive stages among diverse exotic Oryza germplasms can help breeding heat‐resistant rice cultivars.
Zhibin Cao, Huiwu Tang, Yaohui Cai, Bohong Zeng, Jialiang Zhao, Xiuying Tang, Ming Lu, Huimin Wang, Xuejing Zhu, Xiaofeng Wu, Linfeng Yuan, Jianlin Wan   +11 more
wiley   +1 more source

B vitamin supply in plants and humans: the importance of vitamer homeostasis

The Plant Journal, Volume 111, Issue 3, Page 662-682, August 2022., 2022
SUMMARY B vitamins are a group of water‐soluble micronutrients that are required in all life forms. With the lack of biosynthetic pathways, humans depend on dietary uptake of these compounds, either directly or indirectly, from plant sources. B vitamins are frequently given little consideration beyond their role as enzyme accessory factors and are ...
Zeguang Liu, Peter Farkas, Kai Wang, Morgan‐Océane Kohli, Teresa B. Fitzpatrick   +4 more
wiley   +1 more source

ILAE classification and definition of epilepsy syndromes with onset in neonates and infants: Position statement by the ILAE Task Force on Nosology and Definitions

Epilepsia, Volume 63, Issue 6, Page 1349-1397, June 2022., 2022
Abstract The International League Against Epilepsy (ILAE) Task Force on Nosology and Definitions proposes a classification and definition of epilepsy syndromes in the neonate and infant with seizure onset up to 2 years of age. The incidence of epilepsy is high in this age group and epilepsy is frequently associated with significant comorbidities and ...
Sameer M. Zuberi, Elaine Wirrell, Elissa Yozawitz, Jo M. Wilmshurst, Nicola Specchio, Kate Riney, Ronit Pressler, Stephane Auvin, Pauline Samia, Edouard Hirsch, Santiago Galicchio, Chahnez Triki, O. Carter Snead, Samuel Wiebe, J. Helen Cross, Paolo Tinuper, Ingrid E. Scheffer, Emilio Perucca, Solomon L. Moshé, Rima Nabbout   +19 more
wiley   +1 more source

A gene network of uterine luminal epithelium organizes mouse blastocyst implantation

Reproductive Medicine and Biology, Volume 21, Issue 1, January/December 2022., 2022
Abstract Purpose The receptive endometrium is critical for blastocyst implantation. In mice, after blastocysts enter the uterine cavities on day 4 of pregnancy (day 1 = vaginal plug), blastocyst attachment is completed within 24 h, accompanied by dynamic interactions between the uterine luminal epithelium and the blastocysts.
Shizu Aikawa, Yasushi Hirota, Yamato Fukui, Chihiro Ishizawa, Rei IIda, Tetsuaki Kaku, Tomoyuki Hirata, Shun Akaeda, Takehiro Hiraoka, Mitsunori Matsuo, Yutaka Osuga   +10 more
wiley   +1 more source

Sowing forests: a synthesis of seed dispersal and predation by agoutis and their influence on plant communities

Biological Reviews, Volume 96, Issue 6, Page 2425-2445, December 2021., 2021
ABSTRACT Granivorous rodents have been traditionally regarded as antagonistic seed predators. Agoutis (Dasyprocta spp.), however, have also been recognized as mutualistic dispersers of plants because of their role as scatter‐hoarders of seeds, especially for large‐seeded species.
Pedro Mittelman, Caroline Marques Dracxler, Pollyanna R. O. Santos‐Coutinho, Alexandra S. Pires   +3 more
wiley   +1 more source

Clinical research associates experience with missing patient reported outcomes data in cancer randomized controlled trials

Cancer Medicine, Volume 10, Issue 9, Page 3026-3034, May 2021., 2021
This qualitative research provides essential inductive evidence for influences of missing PRO data. The results have important implications for designing operational solutions to improve data quality on cancer RCTs. Abstract Background Missing patient reported outcomes data threaten the validity of PRO‐specific findings and conclusions from randomized ...
Michael J. Palmer, Terry Krupa, Harriet Richardson, Michael D. Brundage   +3 more
wiley   +1 more source

Intellectual Disability Associated With Pyridoxine-Responsive Epilepsies: The Need to Protect Cognitive Development

Frontiers in Psychiatry, 2019
Pyridoxine (vitamin B6)-responsive epilepsies are severe forms of epilepsy that manifest as seizures immediately after birth, sometimes in utero, sometimes months, or years after birth.
Bjørnar Hassel, Bjørnar Hassel, Ane Gretesdatter Rogne, Sigrun Hope   +3 more
doaj   +1 more source

Protein turnover downstream of the Nipbl/CRL4 axis contributes to abnormal development in zebrafish embryos

Developmental Dynamics, Volume 255, Issue 4, Page 403-416, April 2026.
Abstract Background Mutations in cohesins cause cohesinopathies such as Cornelia de Lange Syndrome (CdLS) and Roberts Syndrome (RBS). Prior findings demonstrate that Esco2 (a cohesin activator) and Smc3 (a core cohesin subunit) regulate the CRL4 E3 ubiquitin ligase. SMC3 mutations, however, account for a small percentage of CdLS.
Annie C. Sanchez, Niusha Banoukh, Fiona Mensching, Robert V. Skibbens, M. Kathryn Iovine   +4 more
wiley   +1 more source

The Relationships Among Fear of Missing Out, Problematic Social Media Use, Alexithymia, and Psychiatric Symptoms in Adolescents Attending Psychiatric Outpatient Clinics

Perspectives in Psychiatric Care, Volume 2026, Issue 1, 2026.
Purpose As social media use continues to increase, particularly among adolescents, understanding its impact on mental health is becoming increasingly urgent. This study explored the relationships between alexithymia, fear of missing out (FoMO), excessive social media use, and psychiatric symptoms in a clinical adolescent sample, hypothesizing that ...
Nihal Serdengeçti, Aslı Begüm Can Aydın, Mesut Yavuz, Francisco Sampaio   +3 more
wiley   +1 more source