Results 41 to 50 of about 827,645 (268)

Association of residential greenness with incident chronic obstructive pulmonary disease: A prospective cohort study in the UK Biobank

Environment International, 2023
Background: Residential greenness has been linked to respiratory mortality, but its long-term effect on incident chronic obstructive pulmonary disease (COPD) has rarely been investigated.
Kexin Yu, Qingli Zhang, Xia Meng, Lina Zhang, Haidong Kan, Renjie Chen   +5 more
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Associations between blood cadmium and endocrine features related to PCOS-phenotypes in healthy women of reproductive age: a prospective cohort study [PDF]

, 2021
Keewan Kim, Anna Z. Pollack, Carrie J. Nobles, Lindsey A. Sjaarda, Jessica R. Zolton, Jeannie G. Radoc, Enrique F. Schisterman, Sunni L. Mumford   +7 more
openalex   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

A comparative study in the functional outcomes after conventional Deltopectoral approach vs. anterior deltoid split approach for fixation of proximal humerus fractures

JSES International
Background: Proximal humeral fractures represent 4%-5% of all fractures, with increasing frequencies in the geriatric population due to conditions such as osteoporosis and high-velocity injuries.
Shradha A. Kulkarni, MS Orthopaedics, DNB Orthopaedics, Mansoor Malnas, Postgraduate Student-MS Orthopaedics (final year- 3rd year), Karan Bhanushali, MS Othopaedics, DNB Orthopaedics, Parag K. Munshi, MS Orthopedics, Dorth, DNB, MchOrth, FRCS (Gen Surg), FRCS (Orth)   +3 more
doaj   +1 more source

Trends and Disparities in Lung Cancer and Respiratory Failure Mortality in the United States: A 24‐Year Retrospective Study

Aging and Cancer, EarlyView.
Mortality from lung cancer and respiratory failure in US adults declined until 2010 but increased thereafter, with notable disparities by sex, race, region, and urbanicity. This 24‐year analysis highlights rising post‐2010 mortality in women, non‐Hispanic Whites, and urban areas, underscoring the need for targeted public health interventions.
Sardar M. I. Khan, Muneeb Khawar, Abdul Qadeer, Aqsa Komel, Azka Aisha, Arshia Batool, Ayesha Fatima, Javed Iqbal, Asraf Hussain, Anisha Manzoor, Muhammad Waqas   +10 more
wiley   +1 more source

Serum phthalates and risks of incident cardiovascular disease among individuals with type 2 diabetes in a prospective cohort study

Eco-Environment & Health
Prospective epidemiological evidence about the associations between phthalates (PAEs) and incident cardiovascular disease (CVD) risk among type 2 diabetes mellitus (T2DM) population has been urgently needed.
Shiyang Zhang, Xu Cheng, Chengyong Jia, Jun An, Xin Zhang, Youbing Guan, Yan Yan, Zhuoya Zhao, Yuenan Liu, Tao Jing, Meian He   +10 more
doaj   +1 more source

The Associations Between Chronic Active Lesions and White Matter Disease: A 7 Tesla Imaging Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background The relationship between paramagnetic rim lesions (PRLs) and surrounding normally appearing white matter (NAWM) disease, potentially contributory to the associations seen between PRLs and clinical impairment, is underexplored. Objectives To assess whether PRLs correlate with a greater degree of NAWM injury in early MS.
Ellie McCluey, Ahmad A. Toubasi, Jiacheng Wang, Habeeb F. Kazimuddin, Taegan Vinarsky, Caroline Gheen, Carynn Koch, Zachery Rohm, Bryan Hernandez, Margareta A. Clarke, Rachael Cheek, Rozita Khalili, Chaoyang Jin, Victoria Lim, John Kramer, Junzhong Xu, Ipek Oguz, Francesca Bagnato   +17 more
wiley   +1 more source

Prospective Study of Sleep Talking and Risk of Stroke

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The potential clinical implication of sleep talking in relation to stroke has not been explored to date. This study aimed to prospectively examine the association between sleep talking and the risk of developing stroke in a community‐based ...
Ying Liu, Shuohua Chen, Milena Pavlova, Yaqi Li, Yesong Liu, Jihui Zhang, Liang Sun, Zhenjian Yu, Xiang Gao   +8 more
doaj   +1 more source