Results 161 to 170 of about 732,067 (314)

Future prospects of Qiliqiangxin on heart failure: epigenetic regulation of regeneration

open access: yesFrontiers in Genetics, 2013
Lichan eTAO, Shutong eSHEN, Xinli eLi
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Hospital Administration as an Emerging Specialty for Medical Graduates in India: A Cross-Sectional Study. [PDF]

open access: yesCureus
Sahoo MC   +6 more
europepmc   +1 more source

Artificial Intelligence in the University Educational Process: Student Assessments

open access: yesУправленческое консультирование
Digitalization, aimed at improving the quality of education, is driving a growing need to integrate artificial intelligence (AI) into university teaching.
Yu. N. Lapygin, D. Yu. Lapygin
doaj  

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

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