Results 171 to 180 of about 482,690 (387)

Mass spectrometry in ocular drug research

open access: yesMass Spectrometry Reviews, EarlyView., 2023
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo   +6 more
wiley   +1 more source

Antifertility Properties of Prostaglandin F2α [PDF]

open access: bronze, 1969
Garance Gutknecht   +2 more
openalex   +1 more source

Cutting‐Edge Aptasensing Approaches for Electrochemical Detection of Exosomes Utilizing MXenes

open access: yesChemElectroChem, EarlyView.
This work notably summarizes research on 2D MXenes/MXene's‐hybrid‐based nanoplatforms patterned with aptamers as an alternative to antibodies affording highly sensitive and robust biosensing of exosomes as well as their efficient isolation. The exosomes are highlighted as a valuable source of biomarkers and with the immobilization approaches of ...
Andrej Vikartovský   +5 more
wiley   +1 more source

Investigations into the characterization, degradation, and applications of biodegradable polymers by mass spectrometry

open access: yesMass Spectrometry Reviews, EarlyView., 2023
Abstract Biodegradable polymers have been getting more and more attention because of their contribution to the plastic pollution environmental issues and to move towards a circular economy. Nevertheless, biodegradable materials still exhibit various disadvantages restraining a widespread use in the market.
Paola Rizzarelli   +2 more
wiley   +1 more source

Osteosarcoma Cell and Osteosarcoma Stem Cell Potent Immunogenic Bi‐nuclear Gallium(III) Complexes

open access: yesChemistry – A European Journal, Accepted Article.
We report the synthesis, characterisation, anti‐osteosarcoma and anti‐osteosarcoma stem cells (OSC) properties (cytotoxic and immunogenic) of a series of bi‐nuclear gallium(III) complexes with tridentate Schiff base ligands and 8‐hydroxyquinoline (1‐4).
Xiao Feng   +5 more
wiley   +1 more source

Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production

open access: yesNature Network Boston, 2009
K. Nemeth   +13 more
semanticscholar   +1 more source

Advances in Diclofenac Derivatives: Exploring Carborane‐Substituted N‐Methyl and Nitrile Analogs for Anticancer Therapy

open access: yesChemMedChem, EarlyView.
By N‐methylation, the intramolecular lactam formation in carborane‐substituted diclofenac analogs is prevented, yielding a series of open‐chain derivatives alongside with their phenyl analogs exhibiting anticancer activity and thus offering a promising avenue for future drug development. This study explores the anticancer potential of N‐methylated open‐
Christoph Selg   +12 more
wiley   +1 more source

KEAP1‐NRF2 protein–protein interaction inhibitors: Design, pharmacological properties and therapeutic potential

open access: yesMedicinal Research Reviews, Volume 43, Issue 1, Page 237-287, January 2023., 2023
Abstract The transcription factor nuclear factor erythroid 2‐related factor 2 (NRF2) is considered the master regulator of the phase II antioxidant response. It controls a plethora of cytoprotective genes related to oxidative stress, inflammation, and protein homeostasis, among other processes.
Enrique Crisman   +6 more
wiley   +1 more source

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