Results 201 to 210 of about 482,690 (387)

Role of phospholipase A2 in the stimulation of sponge cell proliferation by homologous lectin. [PDF]

open access: yes, 1989
Friese, K.   +8 more
core   +1 more source

Drug delivery pathways to the central nervous system via the brain glymphatic system circumventing the blood‐brain barrier

open access: yesExploration, EarlyView.
The discovery of the glymphatic system has opened up a pathway for drug delivery to the brain by circumventing the blood‐brain barrier, which can effectively improve drug utilization. The methods of drug delivery through the glymphatic system include intrathecal injection, intranasal injection, and delivery through the meningeal lymphatic vessels.
Xiang Wang   +7 more
wiley   +1 more source

Surface‐Anchored Ticagrelor Gelatin Nanoparticles‐Platelets System for Enhanced Anti‐PD‐L1 Therapy Response and Boosted Chemotherapeutic Efficacy of Nanomedicines

open access: yesExploration, EarlyView.
Ticagrelor nanoparticles modified platelets could adhere to tumor‐associated platelets by specific recruiting ability and responsively release ticagrelor under MMPs stimulation. The released ticagrelor could inhibit platelets activity, enhancing tumor treatment efficacy.
Qi Lu   +12 more
wiley   +1 more source

CYP4F3B is induced by PGA1 in human liver cells: a regulation of the 20-HETE synthesis

open access: yesJournal of Lipid Research, 2008
The regulation of the human liver-specific cytochrome P450 4F3B (CYP4F3B) isoform, a splice variant of the CYP4F3 gene with strong substrate specificity for long chain fatty acids, is yet an unsolved question. This report provides the first evidence that
Joseph Antoun   +6 more
doaj  

Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis

open access: yesNature, 2007
T. North   +13 more
semanticscholar   +1 more source

Spatial Isolation of Single Copper(I) Sites for Cascade Enzyme‐Like Catalysis and Simultaneous Ferroptosis/Cuproptosis Boosted Immunotherapy

open access: yesExploration, EarlyView.
Self‐assembled S‐Cu(I)‐S sites were spatially isolated onto a two‐dimensional Ti3C2 surface to produce a structurally well‐defined and highly functional single‐site copper(I) nanomodulator CuNTD, which can induce severe immunogenic cell death through multiple regulatory pathways of synergistic cascade photothermal‐amplified ROS storms, cuproptosis and ...
Yuanyuan Zhang   +11 more
wiley   +1 more source

Corrigendum: Lipid Bodies as Sites of Prostaglandin E2 Synthesis During Chagas Disease: Impact in the Parasite Escape Mechanism

open access: yesFrontiers in Microbiology, 2018
Patrícia E. de Almeida   +3 more
doaj   +1 more source

Human cyclooxygenase-1 activity and its responses to COX inhibitors are allosterically regulated by nonsubstrate fatty acids

open access: yesJournal of Lipid Research, 2012
Recombinant human prostaglandin endoperoxide H synthase-1 (huPGHS-1) was characterized. huPGHS-1 has a single high-affinity heme binding site per dimer and exhibits maximal cyclooxygenase (COX) activity with one heme per dimer.
Hechang Zou   +6 more
doaj  

Home - About - Disclaimer - Privacy