Results 231 to 240 of about 348,697 (337)

Alterations and mechanistic insights of gut microbiota and its metabolites in type 2 diabetes mellitus and Alzheimer's disease

iMetaOmics, EarlyView.
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu, Yu An, Yage Du, Zhaoming Cao, Jie Zheng, Jingya Wang, Tingyi Li, Xingen Lei, Yanhui Lu   +8 more
wiley   +1 more source

The Role of Lifestyle Intervention in Female Fertility: A Modifiable Factor for Preconception Health. [PDF]

Nutrients
Donato M, Capalbo A, Morizio E, Fratini RM, Pilenzi L, D'Antonio F, Stuppia L, Vitacolonna E, Gatta V, Konstantinidou F.   +9 more
europepmc   +1 more source

The Effects of Epinephrine and Prostaglandin E1 on Cyclic Adenosine 3′ : 5′-Monophosphate Levels in WI-38 Fibroblasts

, 1974
Lewis Kelly, R.W. Butcher
openalex   +1 more source

A Retrospective Analysis of PK and Response of Oral Ibuprofen in the Treatment of a Patent Ductus Arteriosus in Extremely Low Gestational Age Neonates

The Journal of Clinical Pharmacology, EarlyView.
Abstract Oral ibuprofen is the preferred pharmacotherapeutic option for treatment of a persistent patent ductus arteriosus (PDA), but evidence for its optimal use in extremely low gestational age newborns (ELGANs) remains limited. In the current study, we aimed to investigate the pharmacokinetics and exposure‐response relationship of oral ibuprofen in ...
Mohd Asif, Katelyn Sushko, Abdul Razak, Sayem Borhan, Michael Rieder, John van den Anker, Samira Samiee‐Zafarghandy   +6 more
wiley   +1 more source

The Platelet Activation Signaling Pathway Regulated by Fibrinogen and Homo-Gamma-Linolenic Acid (C20:3)-Associated Lipid Metabolism Is Involved in the Maintenance of Early Pregnancy in Chinese Native Yellow Cattle. [PDF]

Animals (Basel)
Yu M, Du C, Ma Y, Ma Y, Li P, Xie X, Li M, Nie X, Liu Y, Hou Y, Miao S, Wang X, Xu J, Yang Y.   +13 more
europepmc   +1 more source

Association between enteral essential fatty acids and plasma phospholipid essential fatty acids related immune response in critically ill adults with COVID‐19: A prospective cohort study

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Coronavirus disease 2019 (COVID‐19) is a complicated disease with widely varying outcomes. Up to 20% of unvaccinated, hospitalized patients infected with COVID‐19 may die during the initial three weeks. Our research shows that COVID‐19 infection results in rapid, remarkable change in the balance between essential fatty acid ...
Vera C. Mazurak, Irma Magaly Rivas‐Serna, Sarah R. Parsons, Md Monirujjaman, Krista E. Maybank, Oleksa G. Rewa, Andrew J. Cave, Caroline Richard, M. Thomas Clandinin   +8 more
wiley   +1 more source

Spatial mapping of the AA-PGE₂-EP axis in multiple sclerosis lesions. [PDF]

Acta Neuropathol
Hansen CE, Konings J, Toth G, Chornyi S, Karsten M, van Het Hof B, van der Pol SMA, Beekhuis-Hoekstra SD, Kok N, Fung WK, Dijksman NS, Baron W, Witte ME, Lanekoff I, de Vries HE, Kooij G.   +15 more
europepmc   +1 more source

Role of Topical Ketoconazole in Therapeutic Hair Care Beyond Seborrhoeic Dermatitis and Dandruff

JEADV Clinical Practice, EarlyView.
ABSTRACT Ketoconazole shampoo has well‐documented consistent efficacy and safety in treating dandruff and seborrhoeic dermatitis (SD) when compared to other active antidandruff ingredients such as selenium sulphide, corticosteroids and zinc pyrithione.
Aditya K. Gupta, Piet De Doncker, Mesbah Talukder   +2 more
wiley   +1 more source

The Patient-Reported Outcomes of Postoperative Prostaglandin E1 Derivative in Lumbar Spine Surgery: A Randomized, Double-Blind, Controlled Trial. [PDF]

Global Spine J
Limthongkul W, Puttasean K, Tanayavong M, Singhatanadgige W, Yingsakmongkol W, Kerr SJ, Kotheeranurak V.   +6 more
europepmc   +1 more source

Preoperative knee joint hypothermia reduces inflammation and recovery time and increases range of motion after total knee arthroplasty: A randomized controlled trial

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Cryotherapy modulates synovial fluid composition by reducing inflammatory mediators and altering metabolite concentrations, resulting in both anti‐inflammatory and anti‐oxidative effects. The aim was to investigate whether preoperative cryocompression would (1) maintain deep tissue hypothermia during the surgical procedure, (2 ...
Leonardo Pieri, Filippo Leggieri, Dimitri Bartoli, Marco Ponti, Chiara Caparrini, Andrea Baldini   +5 more
wiley   +1 more source