Abstract Background Oral non‐steroidal anti‐inflammatory drugs (NSAIDs) are commonly used for analgesia in dogs with spontaneous chronic corneal epithelial defects (SCCEDs). Topical NSAIDs can delay epithelialisation and promote stromal melting, but the safety of systemic NSAIDs in SCCEDs is unknown.
Kaitlyn Scheunemann +2 more
wiley +1 more source
The Role of Papaverine in the Molecular and Biomechanical Mechanisms of Cervical Ripening: A Narrative Review. [PDF]
Flis W, Wartęga M, Góra T, Socha MW.
europepmc +1 more source
Gut microbiota dysbiosis and Long COVID susceptibility in chronic kidney disease
This study investigated gut microbiota dysbiosis and its association with Long COVID susceptibility in 224 hemodialysis patients. We found that 35.3% of patients developed Long COVID, characterized by neurological symptoms and elevated inflammatory markers, accompanied by significant gut microbiota alterations including enriched proinflammatory taxa ...
Meiling Jin +5 more
wiley +1 more source
Endothelin-1 drives COX-2 and prostaglandin E<sub>2</sub> expression in osteoblasts through MAPK/AP-1 signaling during periodontal inflammation. [PDF]
Fan FY +9 more
europepmc +1 more source
ABSTRACT Background Cell senescence (CS) and lipid metabolism (LM) disorders have been reported in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the mechanism is still unclear. Methods Data were obtained from public databases; differential expression analysis and machine learning were performed to identify biomarkers and to understand the
Hui‐Yi Deng +3 more
wiley +1 more source
Understanding Nasal Polyposis: The Roles of Ion Channels, Inflammation, Ionocytes, and Prostaglandin E2-The I<sup>3</sup>PGE<sub>2</sub> Hypothesis. [PDF]
Picado C, Roca-Ferrer J.
europepmc +1 more source
Research Progress on Upper Airway Cough Syndrome
ABSTRACT Upper airway cough syndrome (UACS) has been identified as a significant contributor to chronic cough in various national guidelines. However, the complexity of its pathogenesis, the lack of clarity surrounding its diagnostic criteria, and its overlap with other etiologies of chronic cough present considerable challenges in both diagnosis and ...
Wan‐Ting Huang, Jia Chen
wiley +1 more source
Time-Resolved Metabolomics Reveals Distinct, Cell- and Variety-Dependent Profiles of Prostanoids in Melanoma Cells Exposed to Fruit Extracts from <i>Cornus mas</i> and <i>C. officinalis</i>: A Pilot Study. [PDF]
Lewandowski Ł +12 more
europepmc +1 more source
The Pivotal Role of Plant Derivatives and Eicosanoid Signaling Modulation in Counteracting Cardiomiopathy. [PDF]
Ussia S +13 more
europepmc +1 more source
Prediction of Ocular Toxicity of Prostaglandin F<sub>2α</sub> Analogs Based on Local Computational Models: Superiority over Global Models and Experimental Validation. [PDF]
Lu X +9 more
europepmc +1 more source

