Results 271 to 280 of about 348,697 (337)

Protective Effects of Human Milk Oligosaccharides (hMOs) on Analgesic, Nonsteroidal Anti‐inflammatory Drugs (NSAIDs)‐Induced Disruption of Gut Barrier Integrity in Cocultures Mimicking Neuro‐Gut Epithelial Cell Crosstalk

Molecular Nutrition &Food Research, EarlyView.
Nerve cells partially mitigate indomethacin‐induced tight junction dysregulation in neuro‐gut epithelial cell cocultures. Human milk oligosaccharides 2′‐ and 3‐fucosyllactose (2′‐FL and 3‐FL) protect the neuro‐gut epithelial barrier from indomethacin‐induced damage. This protection is stronger in cocultures with higher nerve cell densities.
Xiaochen Chen, Naschla Gasaly, Marthe T. C. Walvoort, Paul de Vos   +3 more
wiley   +1 more source

Altered polyunsaturated fatty acids and oxylipins profile in Behçet's disease. [PDF]

Korean J Intern Med
Ben-Fradj MK, Naceur I, Talbi E, Wada R, Feki O, Smiti-Khanfir M, Feki M.   +6 more
europepmc   +1 more source

Mitochondrial transfer as a novel therapeutic approach in ischemic stroke treatment: Current challenges and future perspectives

Neuroprotection, EarlyView.
Cerebral ischemia is a serious neurological disease that mainly leads to pathological changes such as mitochondrial dysfunction, oxidative stress and iron death. Mitochondria play a key role in the regulation of cellular energy metabolism and oxidative stress, and their damage can lead to mitochondrial damage, reduced adenosine triphosphate production,
Shuchen Meng, Min Bai, Changsheng Ma, Bo Han, Mengyuan Duan, Liying Zhang, Jinfen Guo, Changku Shi, Ke Li, Maotao He   +9 more
wiley   +1 more source

A phase 2 trial investigating the efficacy and safety of the mPGES-1 inhibitor vipoglanstat in systemic sclerosis-related Raynaud's. [PDF]

Rheumatology (Oxford)
Tornling G, Edenius C, Pauling JD, Denton CP, Olsson A, Kowalski J, Murray A, Anderson M, Bhat S, Del Galdo F, Hall F, Korkosz M, Krasowska D, Olas J, Smith V, van Laar JM, Vonk MC, Wojteczek A, Herrick AL.   +18 more
europepmc   +1 more source

Role of astrocyte in neuroinflammation‐induced loss in neuroplasticity and subsequent onset of depression: A systematic review

Neuroprotection, EarlyView.
Mechanistic crosstalk between microglia and astrocytes in major depressive disorder. Abstract Major depressive disorder (MDD) is a complex psychiatric condition increasingly linked to chronic neuroinflammation, particularly in the context of aging, stress, and systemic comorbidities.
Gaurav Singhal, Saurabh Singhal, Bernhard T. Baune   +2 more
wiley   +1 more source

Effects of low-frequency and high-frequency electroacupuncture pretreatment on the COX-2/mPGES-1/PGE2 pathway in a rat model of cold-coagulation dysmenorrhea. [PDF]

Front Immunol
Song Y, Ni J, Yuan J, Zhang Z, Wang D, Xiong Z.   +5 more
europepmc   +1 more source

Steroids for Pediatric Adenotonsillectomy Pain—A Prospective Multicenter Randomized Trial

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To compare postoperative caregiver‐reported pain control of two steroid regimens following pediatric adenotonsillectomy. Secondary objectives assessed differences in analgesic use, return to normal diet, caregiver calls, adverse effects, and emergency room (ER) visits. Study Design Prospective randomized pragmatic trial.
Kevin D. Pereira, Wiktoria A. Gocal, Anna V. Borodianski, Mary E. Williamson, Hengameh K. Behzadpour, Sonal Saraiya, Diego A. Preciado, Amal Isaiah   +7 more
wiley   +1 more source

Pharmacogenetic Influences on Individual Responses to Ocular Hypotensive Agents in Glaucoma Patients. [PDF]

Pharmaceutics
Labay-Tejado S, Fortuna V, Ventura-Abreu N, Hernaez M, Opazo-Toro V, Garcia-Humanes A, Brunet M, Milla E.   +7 more
europepmc   +1 more source

Systemic adverse drug events to topical prostaglandin analogs for treating glaucoma: a retrospective focused pharmacovigilance study. [PDF]

BMC Ophthalmol
Sridharan K.
europepmc   +1 more source

Profiling the Anti-Photoaging Impact of Titanium Dioxide and Zinc Oxide Nanoparticles: A Focus on Signaling Pathways. [PDF]

FASEB J
Pangilinan NDT, Shalbaf M, Souza A, Chavan B, Bonn C, Birch-Machin MA.   +5 more
europepmc   +1 more source