Results 251 to 260 of about 185,296 (332)

Angiogenesis as a Therapeutic Target of (Poly)phenols: Tackling Cancer and Vascular‐Related Complications

open access: yesMolecular Nutrition &Food Research, EarlyView.
(Poly)phenols constitute a source of natural therapeutic molecules capable of targeting angiogenesis in different scenarios. This review summarizes the current evidence of the role of (poly)phenols in modulating angiogenesis. The reader can find a compilation of preclinical and human investigations describing pro‐ and anti‐angiogenic effects of these ...
María Ángeles Ávila‐Gálvez   +5 more
wiley   +1 more source

Protective Properties of the White Button Mushroom, Agaricus bisporus, in a Mouse Model of Colitis

open access: yesMolecular Nutrition &Food Research, EarlyView.
In this study, whole mushroom powder (WMP) from white button mushrooms was tested for gut health benefits. In vitro digested WMP (IVD‐WMP) could reduce the permeability of a gastrointestinal cell layer. In mouse studies, WMP was tested as a preventative and a treatment for dextran sulfate sodium (DSS) induced colitis. WMP could improve recovery, reduce
Elaine Dempsey   +5 more
wiley   +1 more source

Protective Effects of Human Milk Oligosaccharides (hMOs) on Analgesic, Nonsteroidal Anti‐inflammatory Drugs (NSAIDs)‐Induced Disruption of Gut Barrier Integrity in Cocultures Mimicking Neuro‐Gut Epithelial Cell Crosstalk

open access: yesMolecular Nutrition &Food Research, EarlyView.
Nerve cells partially mitigate indomethacin‐induced tight junction dysregulation in neuro‐gut epithelial cell cocultures. Human milk oligosaccharides 2′‐ and 3‐fucosyllactose (2′‐FL and 3‐FL) protect the neuro‐gut epithelial barrier from indomethacin‐induced damage. This protection is stronger in cocultures with higher nerve cell densities.
Xiaochen Chen   +3 more
wiley   +1 more source

Prospects for lentiviral vector mediated prostaglandin F synthase gene delivery in monkey eyes in vivo. [PDF]

open access: yesCurr Eye Res, 2014
Lee ES   +8 more
europepmc   +1 more source

Exploring the Impact of a High‐Fat Diet on Brain Homeostasis: A Comprehensive Analysis of the Absence of Inflammation

open access: yesMolecular Nutrition &Food Research, EarlyView.
Male and female mice were fed different diets for up to 24 weeks to study the effects of phytosterols (PS) on weight gain and brain immune cells. PS reduced weight gain in HFD‐fed mice. Microglia were isolated from brains and analyzed, revealing no diet‐driven inflammation changes, but differences based on sex and age.
Laura Plantera   +7 more
wiley   +1 more source

Mitochondrial transfer as a novel therapeutic approach in ischemic stroke treatment: Current challenges and future perspectives

open access: yesNeuroprotection, EarlyView.
Cerebral ischemia is a serious neurological disease that mainly leads to pathological changes such as mitochondrial dysfunction, oxidative stress and iron death. Mitochondria play a key role in the regulation of cellular energy metabolism and oxidative stress, and their damage can lead to mitochondrial damage, reduced adenosine triphosphate production,
Shuchen Meng   +9 more
wiley   +1 more source

Prostaglandin F-induced Prostate Transmembrane Protein, Androgen Induced 1 mediates ovarian cancer progression increasing epithelial plasticity. [PDF]

open access: yesNeoplasia, 2019
Jiménez-Segovia A   +13 more
europepmc   +1 more source

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