Results 271 to 280 of about 9,774,870 (350)

Oxytocin Receptor Antagonists, Atosiban and Nolasiban, Inhibit Prostaglandin F-induced Contractions and Inflammatory Responses in Human Myometrium. [PDF]

open access: yesSci Rep, 2019
Kim SH   +8 more
europepmc   +1 more source

Prototype master protocol for benchmarking of real‐world follow‐up data in glaucoma

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose The purpose of this study was to create a prototype master protocol for benchmarking glaucoma real‐world data (RWD). Benchmarking is part of the digital innovation strategy of the Finnish aces‐rwm ecosystem (automation of care and evaluation of the system with real‐world monitoring).
Pekko Hujanen   +7 more
wiley   +1 more source

Sex differences in the vasoactive effect of transient receptor potential channels: TRPM3 as a new therapeutic target for (neuro)vascular disorders

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Sex‐dependent vascular effects of transient receptor potential (TRP) channels and sex dimorphism in migraine are not yet fully characterized. We investigated the differential vasoactive effects of TRP ankyrin 1 (TRPA1), TRP melastatin 3 (TRPM3) and TRP vanilloid 1 (TRPV1) channels, their pharmacological mechanism(s), and
Eduardo Rivera‐Mancilla   +7 more
wiley   +1 more source

Systemic EP4 receptor agonist and Arginase‐1 therapy in a murine model of chronic asthma and influenza virus‐induced asthma exacerbation

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Myeloid‐derived suppressor cells (MDSCs) play important roles in the pathogenesis of asthma. Recent studies demonstrate that their function can be modulated by different pharmacological approaches. In this study, we focussed on the effects of systemically administered prostaglandin EP4 receptor agonist L‐902,688 and pegylated ...
Tim Lange   +7 more
wiley   +1 more source

Metabolomic effects of intrauterine meloxicam perfusion on histotroph in dairy heifers during diestrus. [PDF]

open access: yesFront Vet Sci
Zhang B   +8 more
europepmc   +1 more source

Circulating Mast Cell Progenitors Are Depleted by Benralizumab in Severe Asthma

open access: yes
Allergy, EarlyView.
Michael Fricker   +3 more
wiley   +1 more source

Ibuprofen inhibits human sweet taste and glucose detection implicating an additional mechanism of metabolic disease risk reduction

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose The human sweet taste receptor, TAS1R2–TAS1R3, conveys sweet taste in the mouth and may help regulate glucose metabolism throughout the body. Ibuprofen and naproxen are structurally similar to known inhibitors of TAS1R2–TAS1R3 and have been associated with metabolic benefits.
Emily C. Hanselman   +6 more
wiley   +1 more source

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