Hypothyroidism Affects Uterine Function via the Modulation of Prostaglandin Signaling
Thyroid hormones control the functions of almost all body systems. Reproductive dysfunctions, such as abnormal sexual development, infertility, or irregularities in the reproductive cycle, might be associated with thyroid disorders.
Ilona Kowalczyk-Zieba+5 more
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The liver is a key metabolic organ that is particularly sensitive to environmental factors, including UV radiation. As UV radiation induces oxidative stress and inflammation, natural compounds are under investigation as one method to counteract these ...
Michał Biernacki+2 more
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Effect of prostaglandin on reproduction in relation to pituitary gonadal axis in the fish, Cyprinus carpio (L.) [PDF]
Prostaglandins are a class of fatty acids which are “traditionally” associated with a variety of autocrine and paracrine functions in the vertebrate body.
Dabhade, R.C.+2 more
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Influence of dietary linoleic acid intake with different fat intakes on arachidonic acid concentrations in plasma and platelet lipids and eicosanoid biosynthesis in female volunteers [PDF]
Background/Aim: N-6 fatty acids are considered to promote diseases prevalent in industrialized countries and characterized by an increased eicosanoid biosynthesis from arachidonic acid (AA).
Adam, Olaf, Wolfram, G., Zöllner, N.
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Polyunsaturated fatty acid-derived lipid mediators and T cell function [PDF]
Copyright © 2014 Nicolaou, Mauro, Urquhart and Marelli-Berg . This is an open- access article distributed under the terms of the Creative Commons Attribution License (CC BY) .
Marelli-Berg, F+3 more
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Intrauterine devices (IUDs) are used in mares to suppress oestrous behaviour, but the underlying mechanism is yet to be elucidated. The presence of an embryo or an IUD prevents cyclooxygenase-2 (COX-2) and, subsequently, prostaglandin (PG) release and ...
Maria Montserrat Rivera del Alamo+5 more
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Kinetic mechanism of ketoreductase activity of prostaglandin F synthase from bovine lung [PDF]
The kinetic mechanism of ketoreductase activity of bovine lung prostaglandin F synthase, expressed in E. coli, was investigated. Data on initial velocity and radioisotope exchange between [3H]prostaglandin D; and 9α, 11β-prostaglandin F2 suggest that the
Barski, Oleg A., Watanabe, Kikuko
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Human prostaglandin EP3 receptor isoforms show different agonist-induced internalization patterns [PDF]
The human prostaglandin EP3 receptor comprises eight isoforms that differ in carboxyl-tail. We show here that the isoforms are trafficked differently. When expressed in HEK293 cells, the isoforms located to the cell surface, although a fraction of some ...
Ashby, Barrie+2 more
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A comparative study between prostaglandin F2α and methyl ergometrine in the active management of third stage of labour [PDF]
Objective: The aim of the study is to see the efficacy and safety of intramuscular Prostaglandin F 2α versus intravenous Methyl Ergometrine in active management of third stage labor. Material and Methods: A prospective study was carried out over a period
Sabha Malik+2 more
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N-Alkylation and N-acylation of the prostaglandin-F2α allosteric modulator l-PDC31 were performed to install various alkyl, PEG and isoprenoid groups onto the l-enantiomer of the peptide.
Julien Poupart+3 more
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