Results 41 to 50 of about 9,739,564 (270)

Preparation of Prostaglandin F from Prostaglandin E. Prostaglandins and Related Factors. 6. [PDF]

Acta Chemica Scandinavica, 1962
Reduction of prostaglandin E (PGE) with sodium borohydride yielded 2 compounds 1 of which is identical with PGF isolated from the prostate of sheep and the other of which had different physical and biological properties but the same elementary composition. The former was designated PGF1 and the latter PGF2.
Olof Theander, Sune Bergström, Lennart Krabisch, Benny Samuelsson, H. Flood, J. Sjövall   +5 more
openaire   +2 more sources

Development of Potent and Selective Indomethacin Analogues for the Inhibition of AKR1C3 (Type 5 17β-Hydroxysteroid Dehydrogenase/Prostaglandin F Synthase) in Castrate-Resistant Prostate Cancer

Journal of Medicinal Chemistry, 2013
Castrate-resistant prostate cancer (CRPC) is a fatal, metastatic form of prostate cancer. CRPC is characterized by reactivation of the androgen axis due to changes in androgen receptor signaling and/or adaptive intratumoral androgen biosynthesis.
A. Liedtke, A. Adeniji, Mo Chen, Michael C. Byrns, Yi Jin, D. Christianson, L. Marnett, T. Penning   +7 more
semanticscholar   +1 more source

Effect of prostaglandin F2α &oxyotocin on semen charistrics of alawassi ram

Kufa Journal for Veterinary Medical Sciences, 2013
The study was conducted at the Faculty of Veterinary Medicine / University of Qadisiyah five Awassi Rams converged for the purpose of reconstruction see the effect of injection hormone prostaglandin F2α  and oxytocin in semen recipes for Awassisheep ...
Abdul Hussein Thyab Shoaibeth, Dhia Hussain Jassim Al-Dulamy   +1 more
doaj   +1 more source

Prostaglandin F in the Fallopian Tube Secretion of the Ewe [PDF]

Australian Journal of Biological Sciences, 1978
Oviducal secretions were obtained from conscious unrestrained ewes throughout the oestrous cycle via indwelling cannulae and the content of prostaglandin F (pGF) was determined by radioimmunoassay. Levels of PGF of up to 230 ngjml were found in oviducal fluids obtained from ewes showing regular patterns of secretion and normal cyclical ovarian function
F. Amato, Robert F. Seamark, GM Warnes
openaire   +3 more sources

Oxidative stress-dependent cyclooxygenase-2-derived prostaglandin f(2α) impairs endothelial function in renovascular hypertensive rats.

Antioxidants and Redox Signaling, 2012
UNLABELLED Abstract Aims: The role of endothelium-derived contracting factors (EDCFs) in regulating renovascular function is yet to be elucidated in renovascular hypertension (RH).
X. Tian, W. Wong, F. Leung, Yang Zhang, Yi-xiang Wang, H. Lee, C. Ng, Z. Chen, X. Yao, C. Au, C. Lau, P. Vanhoutte, J. Cooke, Yu Huang   +13 more
semanticscholar   +1 more source

F-Prostaglandin receptor regulates endothelial cell function via fibroblast growth factor-2

BMC Cell Biology, 2010
Background Prostaglandin (PG) F2α is a key regulator of endometrial function and exerts its biological action after coupling with its heptahelical G protein-coupled receptor (FP receptor).
Jabbour Henry N, Brown Pamela, Keightley Margaret C, Sales Kurt J   +3 more
doaj   +1 more source

Do Seminal Isoprostanes Have a Role in Assisted Reproduction Outcome?

Life, 2021
F2-isoprostanes (F2-IsoPs), stereoisomers of prostaglandin F2α generated by the free radical-induced oxidation of arachidonic acid, have been associated with different male infertility conditions.
Giulia Collodel, Daria Noto, Cinzia Signorini, Laura Gambera, Anita Stendardi, Amra Mahmutbegovic, Lucia Micheli, Andrea Menchiari, Elena Moretti   +8 more
doaj   +1 more source

The human aldose reductase AKR1B1 qualifies as the primary prostaglandin F synthase in the endometrium.

Journal of Clinical Endocrinology and Metabolism, 2011
CONTEXT Prostaglandins (PGs) E2 and PGF2α are produced in the endometrium and are important for menstruation and fertility. Dysmenorrhea is associated with increased production of PGF2α relative to PGE2, and the opposite is true for menorrhagia.
Eva Bresson, S. Boucher-Kovalik, P. Chapdelaine, É. Madore, N. Harvey, P. Laberge, M. Leboeuf, M. Fortier   +7 more
semanticscholar   +1 more source

Genes for prostaglandin synthesis, transport and inactivation are differentially expressed in human uterine tissues, and the prostaglandin F synthase AKR1B1 is induced in myometrial cells by inflammatory cytokines.

Molecular human reproduction, 2011
Prostaglandins (PGs) are important factors in the physiology of human parturition and the control of uterine contractility. We have characterized the expression of 15 genes from all stages of the PG pathway in human pregnant and non-pregnant (NP ...
Robert J. Phillips, H. Al-Zamil, Linda P. Hunt, Michel A. Fortier, A. L. Bernal   +4 more
semanticscholar   +1 more source

Transport of prostaglandin F(2alpha) pulses from the uterus to the ovary at the time of luteolysis in ruminants is regulated by prostaglandin transporter-mediated mechanisms.

Endocrinology, 2010
In ruminants, prostaglandin F2alpha (PGF(2alpha)) is the uterine luteolytic hormone. During luteolysis, PGF(2alpha) is synthesized and released from the endometrium in a pulsatile pattern.
JeHoon Lee, J. Mccracken, S. Banu, R. Rodriguez, Thamizh K. Nithy, J. Arosh   +5 more
semanticscholar   +1 more source