Results 191 to 200 of about 131,150 (281)

Chromophore conformation in biliproteins [PDF]

, 1979
Formanek, H., Rüdiger, W., Scheer, Hugo
core  

Energetic microdomains and the vascular control of neuronal and muscle excitability: Toward a unified model

The Journal of Physiology, EarlyView.
Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
wiley   +1 more source

Design, synthesis, characterization, biological investigation and docking studies of newly synthesized sulphonyl hydrazide and their derivatives. [PDF]

Sci Rep
Rahman M, Zafar R, Jan MS, Darwish HW, Khattak H, Aschner M, Daglia M, Khan H.   +7 more
europepmc   +1 more source

NSAID ingestion augments training‐induced muscle hypertrophy and differentially affects muscle mRNA expression, but not strength gains, in trained men

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the impact of NSAID ingestion on resistance exercise training‐induced changes in muscle morphology, function and gene networks relative to placebo ingestion in trained males. Abstract Non‐steroidal anti‐inflammatory drugs (NSAIDs) are widely overused in sports.
Joanne E. Mallinson, Tariq Taylor, Dumitru Constantin‐Teodosiu, Despina Constantin, Martino V. Franchi, Dorothee Auer, Paul L. Greenhaff   +6 more
wiley   +1 more source

Regulatory grammar in human promoters uncovered by MPRA-based deep learning. [PDF]

Nature
Barbadilla-Martínez L, Klaassen N, Franceschini-Santos VH, Breda J, Yücel H, Hernández-Quiles M, van Lieshout T, Urzua Traslaviña CG, Boi MCL, Akbarzadeh M, Hermana-Garcia-Agullo C, Gregoricchio S, de Haas M, Straver R, Derks S, Zwart W, Voest E, Franke L, Vermeulen M, de Ridder J, van Steensel B.   +20 more
europepmc   +1 more source

Cytoprotection by Prostaglandins in Rats Prevention of Gastric Necrosis Produced by Alcohol, HCl, NaOH, Hypertonic NaCl, and Thermal Injury

, 1979
A. Robert, J. E. Nezamis, C. Lancaster, A. Hanchar   +3 more
semanticscholar   +1 more source

Treating age‐related loss of muscle mass and function: Where should we be focusing?

The Journal of Physiology, EarlyView.
Abstract figure legend Perturbations contributing to the age‐related loss of muscle mass and strength. A, in the spinal cord, self‐reinforcing cycles of oxidative stress, mitochondrial dysfunction and inflammation mediated by cells, including microglia, contribute to motor neuron degeneration.
Daniel J. Ham, Christopher S. Fry, Avnika Ashok Ruparelia, Shyuan T. Ngo, Séverine Lamon   +4 more
wiley   +1 more source

Stimulation of Transient Receptor Potential Channels TRPM3 and TRPM8 Increases Human Prostaglandin Endoperoxide Synthase-2 Promoter Activity. [PDF]

Molecules
Brandmeier N, Rössler OG, Thiel G.
europepmc   +1 more source

TRIP8bnano peptide prevents cAMP binding to HCN2 channels alleviating pain‐like behaviors in rats with neuropathic pain

The Journal of Physiology, EarlyView.
Abstract figure legend We tested the hypothesis that cAMP binding to HCN2 channels in nociceptors is a causal driver of neuropathic pain by using TRIP8bnano, a synthetic peptide we previously developed as a selective antagonist of cAMP in HCN channels. TRIP8bnano effectively abolishes cAMP potentiation of HCN2 currents in small‐diameter DRG neurons and
Santiago I. Loya‐Lopez, Kimberly Gomez, Alessandro Porro, Gerhard Thiel, Anna Moroni, Heather N. Allen, Rajesh Khanna, Andrea Saponaro   +7 more
wiley   +1 more source

Downregulation of MGST3 promotes colorectal cancer progression. [PDF]

Mol Clin Oncol
Wu Y, Fan C, Zhou J, Huang F, Zhang Y, He Y, Wang J.   +6 more
europepmc   +1 more source