Results 221 to 230 of about 131,150 (281)

Editorial: What does experimental pharmacology and drug discovery look like in 2035? [PDF]

Front Pharmacol
Fabbrini MS, Vago R.
europepmc   +1 more source

Prostaglandin analogues signal detection by data mining in the FDA Adverse Event Reporting System database. [PDF]

BMJ Open Ophthalmol
Contreras-Salinas H, Romero-López MS, Olvera-Montaño O, Rodríguez-Herrera LY.   +3 more
europepmc   +1 more source

Physiological roles of fatty acids and endocannabinoids in the nematode Caenorhabditis elegans [PDF]

Reisner, Kaja
core  

4-Hydroxycoumarin Exhibits Antinociceptive and Anti-Inflammatory Effects Through Cytokine Modulation: An Integrated In Silico and In Vivo Study. [PDF]

Int J Mol Sci
da Fonsêca DV, Rocha JS, da Silva PR, de Sá Novaes Pereira HN, Dos Santos LVN, de Santana MAD, Alves AF, Pontes AHO, de Souza Gomes J, Felipe CFB, de Sousa DP, Scotti MT, Scotti L.   +12 more
europepmc   +1 more source

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Mass spectrometric determination of picomole amounts of prostaglandins E2 and F2α using synthetic deuterium labeled carriers

Biochemical and Biophysical Research Communications, 1971
Abstract [3,3,4,4-D 4 ]-prostaglandin E 2 and [3,3,4,4-D 4 ]-prostaglandin F 2α were prepared and used as carriers in quantitative gas chromatography-mass spectrometry. Ions of the protium form and the tetradeuterio form produced by electron impact on the effluent were monitored.
U, Axen, K, Gréen, D, Hörlin, B, Samuelsson   +3 more
openaire   +3 more sources

Dermatological adverse effects of anti‐glaucoma eye drops: a review

Journal of the European Academy of Dermatology and Venereology, 2022
Many patients are treated for glaucoma. Like other drugs, anti‐glaucoma eye drops may induce dermatological adverse effects. We aim to review the dermatological adverse effects secondary to the active agents in anti‐glaucoma eye drops through a ...
Alexandra Patchinsky, Nadine Petitpain, Pierre Gillet, K. Angioi-Duprez, Jean-Luc Schmutz, A. Bursztejn   +5 more
semanticscholar   +1 more source

Synthetic Modification of Prostaglandin F2α Indicates Different Structural Determinants for Binding to the Prostaglandin F Receptor Versus the Prostaglandin Transporter

Molecular Pharmacology, 2000
Several principles governing the binding of E series prostaglandins to EP receptors have emerged in recent years. The C-1 carboxyl group binds electrostatically to a conserved arginine residue in the seventh transmembrane segment of the receptor. Prostaglandin E analogs involving bioisosteric replacements of the carboxyl group, such as acylsulfonamide,
V L, Schuster, S, Itoh, S W, Andrews, R M, Burk, J, Chen, K M, Kedzie, D W, Gil, D F, Woodward   +7 more
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THE TERMINATION OF PREGNANCY BY INTRAVENOUS INFUSION OF A SYNTHETIC PROSTAGLANDIN F_2α ANALOGUE

BJOG: An International Journal of Obstetrics & Gynaecology, 1973
SummaryA synthetic analogue of prostaglandin F2α was successfully used to induce abortion in six patients, five of whom were in the second trimester of pregnancy. Five of the patients had a complete abortion and in one the abortion was incomplete. The mean induction‐abortion interval was 25 hours 15 minutes, ranging from 7 hours 45 minutes to 49 hours ...
D S, Sharp, R W, Burslem
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Therapeutic uses of prostaglandin F2α analogues in ocular disease and novel synthetic strategies

Prostaglandins & Other Lipid Mediators, 2013
The pharmacological management of glaucoma and ocular hypertension has significantly changed over the last 18 years with the introduction of PGF2α analogues, more specifically latanoprost (6), travoprost (8), bimatoprost (10) and tafluprost (12). Prostanoids are currently the first-line medicines among ocular antihypertensive drugs in terms of efficacy,
Iwona, Dams, Jaromir, Wasyluk, Marek, Prost, Andrzej, Kutner   +3 more
openaire   +2 more sources