Results 171 to 180 of about 1,302,201 (345)

Deep Docking: A Deep Learning Platform for Augmentation of Structure Based Drug Discovery

open access: yesACS Central Science, 2020
Francesco Gentile   +7 more
doaj   +1 more source

At the Pointy End of Mechanobiology: AFM for Transient Biomechanical Analysis

open access: yesAdvanced Healthcare Materials, EarlyView.
Stem cell mechanosensitivity governs lineage commitment through mechanotransduction, but capturing these transient changes in living cells remains challenging. Advanced atomic force microscopy enables high‐resolution analysis of mechanical properties, real‐time protein distribution, and gene expression, offering fresh insights into cell‐environment ...
Kaiwen Zhang   +5 more
wiley   +1 more source

AR-V7 and resistance to enzalutamide and abiraterone in prostate cancer.

open access: yesNew England Journal of Medicine, 2014
E. Antonarakis   +20 more
semanticscholar   +1 more source

Transforming Cancer Diagnosis and Therapy Through Fluorescent Hydrogels: A Review

open access: yesAdvanced Healthcare Materials, EarlyView.
This article reviews fluorescent hydrogel systems for cancer detection, monitoring, and therapy. Mimicking the tumor microenvironment, these hydrogels enable real‐time imaging and targeted drug delivery. The review discusses design strategies, labeling techniques, and applications, highlighting challenges and future opportunities in cancer diagnostics ...
Elahe Masaeli   +2 more
wiley   +1 more source

Integrin β4‐Enriched Small Extracellular Vesicle as Drug Delivery Vehicle for Targeting Pulmonary Metastasis of Hepatocellular Carcinoma

open access: yesAdvanced Healthcare Materials, EarlyView.
The expression of integrin β4 (ITGβ4) on small extracellular vesicle (sEV) correlates with lung‐tropism. Enrichment of ITGβ4 on sEVs enhances their lung‐targeting ability. The sEVs loaded with doxorubicin exhibit superior therapeutic efficacy in a lung metastasis mouse model.
Tung Him Ng   +7 more
wiley   +1 more source

Cribriform pattern and IDC-P in prostate biopsies: prognostic relevance and reporting in metastatic disease. [PDF]

open access: yesJ Pathol Clin Res
Okubo Y   +16 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy