Results 281 to 290 of about 1,476,150 (337)

18 F-FDG PET/CT in Rhabdomyosarcoma of the Prostate in an Infant. [PDF]

open access: yesClin Nucl Med
Schweighofer N   +5 more
europepmc   +1 more source

A20 Facilitates Oxaliplatin Sensitivity in Colorectal Cancer Through Monoubiquitylation of IKK‐β

open access: yesAdvanced Science, EarlyView.
This study demonstrates that the expression of A20, a ubiquitin‐editing enzyme, is positively correlated with oxaliplatin sensitivity in colorectal cancer (CRC). Mechanistically, A20 enhances oxaliplatin sensitivity by inhibiting NF‐κB nuclear translocation through monoubiquitination of IKK‐β.
Fan Luo   +12 more
wiley   +1 more source

Clonal evolution and transcriptional plasticity shape metastatic dissemination routes in prostate cancer. [PDF]

open access: yesNat Commun
Mikutenaite M   +17 more
europepmc   +1 more source

scPER: A Rigorous Computational Approach to Determine Cellular Subtypes in Tumors Aligned With Cancer Phenotypes From Total RNA Sequencing

open access: yesAdvanced Science, EarlyView.
scPER presents an adversarial‐autoencoder framework that deconvolves bulk total RNA‐seq to quantify tumor‐microenvironment cell types and uncover phenotype‐linked subclusters. Across diverse benchmarks, scPER improves accuracy over existing tools.
Bingrui Li, Xiaobo Zhou, Raghu Kalluri
wiley   +1 more source

PTBP1 Regulates DNMT3B Alternative Splicing by Interacting With RALY to Enhance the Radioresistance of Prostate Cancer

open access: gold
Haixia He   +18 more
openalex   +1 more source

Cancer Manipulates Adjacent Adipose Tissue to Exploit Fatty Acids via HIF‐1α/CCL2/PPARα Axis: A Metabolic Circuit to Support Tumor Progression

open access: yesAdvanced Science, EarlyView.
Cancer cells drive adjacent adipose tissue to release fatty acids by secreting CCL2, which activates PPARα‐dependent lipolysis. The resulting fatty acid influx amplifies HIF‐1α/CCL2 signaling, establishing a positive feedback loop that fuels tumor growth.
Jeong‐Eun Yun   +9 more
wiley   +1 more source

Prostate cancer cells converge to an inflammatory-like state upon metastatic dissemination. [PDF]

open access: yesNat Commun
Keshavarzian T   +21 more
europepmc   +1 more source

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