Results 331 to 340 of about 1,807,537 (411)

A 3D Genome Atlas of Genetic Variants and Their Pathological Effects in Cancer

open access: yesAdvanced Science, EarlyView.
The hierarchical organization of the eukaryotic genome is vital for nuclear function, and disruptions from genetic mutations can alter this 3D architecture. Cataloging thousands of interchromosomal translocations, structural variants, and single nucleotide polymorphisms, their impact on 3D genome organization is revealed. The scoring algorithm, 3DFunc,
Li Tang   +6 more
wiley   +1 more source

Machine Learning‐Based Radiomics in Malignancy Prediction of Pancreatic Cystic Lesions: Evidence from Cyst Fluid Multi‐Omics

open access: yesAdvanced Science, EarlyView.
This study develops noninvasive clinical‐radiomic models using preoperative CT images to predict the malignant potential of pancreatic cystic lesions. It demonstrates the models' high accuracy across various datasets, with AUCs exceeding 0.92. Additionally, multi‐omics analyses uncover key biological mechanisms, including secretion function and lipid ...
Sihang Cheng   +14 more
wiley   +1 more source

Deep learning for quality assessment of axial T2-weighted prostate MRI: a tool to reduce unnecessary rescanning. [PDF]

open access: yesEur Radiol Exp
Gloe JN   +7 more
europepmc   +1 more source

Osteosarcoma Cell‐Derived Migrasomes Promote Macrophage M2 Polarization to Aggravate Osteosarcoma Proliferation and Metastasis

open access: yesAdvanced Science, EarlyView.
Migrasomes are newly discovered organelles in migrating cells. This study finds that osteosarcoma cell‐derived migrasomes promote the tumor‐promoting phenotype of macrophages and further aggravate osteosarcoma malignant progression via milk fat globule‐EGF factor 8.
Wanshun Liu   +10 more
wiley   +1 more source

Diagnostic Significance of Serum Ferritin and Hepcidin as Complementary Biomarkers for Prostate Disease: A Prospective Case-Control Study in a Mission Hospital, Ghana. [PDF]

open access: yesHealth Sci Rep
Appiah SK   +20 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy