Results 291 to 300 of about 1,150,712 (337)

Integrative genomic and bioinformatic prioritization of drug repurposing candidates for prostate cancer. [PDF]

BMC Pharmacol Toxicol
Irham LM, Adikusuma W, Afief AR, Khairi S, Chong R, Mufidah S, Satria RD, Mugiyanto E, Darmawi D, Amukti DP, Wirsahada BC, Philothra PT, Jaya I.   +12 more
europepmc   +1 more source

Single‐Cell Analysis Reveals that Vitamin C Inhibits Bone Metastasis of Renal Cancer via Cell Cycle Arrest and Microenvironment Remodeling

Advanced Science, EarlyView.
3D‐cultured renal cancer cells exhibit stem‐like phenotypes and are more efficient in generating bone metastases. Vitamin C treatment can suppress the development of bone metastasis. Single‐cell transcriptomic analysis reveals that vitamin C inhibits metastasis by inducing tumor cell cycle arrest, suppressing osteoclast differentiation, and reducing ...
Jianye Zhang, Qi Zhang, Gang Lin, Ying Wang, Juan Li, Ping Wang, Jie Qi, Yuan Liang, Shiming He, Yanqing Gong, Ninghan Feng, Yang Wang, Yuanyuan Ma, Mei Zhang, Yue Shi, Xuesong Li, Weimin Ci, Liqun Zhou   +17 more
wiley   +1 more source

AUA Guidelines for Screening of Prostate Cancer 2023.

J Pharm Bioallied Sci
Agrawal R, Sabale VP, Ahmad S.
europepmc   +1 more source

A Super‐Enhancer‐Driven Transcriptional Regulatory Circuit Underlying Abiraterone Resistance in Castration‐Resistant Prostate Cancer

Advanced Science, EarlyView.
This study identifies a super‐enhancer‐driven transcriptional regulatory circuit comprising BCL6, SMAD3, and NFIB that cooperate to drive cholesterol synthesis via SREBF2/HMGCR/FDFT1 activation and regulate CDK2/CCND3 for cell cycle control. Targeting this circuit with BI‐3802 or downstream inhibitors (Fatostatin/Lovastatin) overcomes abiraterone ...
Liling Jiang, Jiamin Wang, Guanjie Peng, Haichuan Zhang, Jinxin Fang, Yingyin Gao, Enzhe Lou, Yangzhou Liu, Wa Ding, Bingyuan Liu, Qiong Mao, Lizhen Jiang, Aochu Liu, Xinyue Li, Shiwen Hu, Qiaomin Ma, Yueyuan Zheng, Zhigang Zhao, Xianping Shi   +18 more
wiley   +1 more source

Correction: The PP2A regulator IER5L supports prostate cancer progression. [PDF]

Cell Death Dis
Crespo JR, Martín-Martín N, Garcia-Longarte S, Corres-Mendizabal J, Carlevaris O, Astobiza I, Zabala-Letona A, Guiu M, Azkargorta M, Gonzalez-Lopez M, Macías-Cámara N, Doan P, Elortza F, Mendizabal I, Westermarck J, Gomis RR, Ercilla A, Carracedo A.   +17 more
europepmc   +1 more source

Testosterone Delays Bone Microstructural Destruction via Osteoblast‐Androgen Receptor‐Mediated Upregulation of Tenascin‐C

Advanced Science, EarlyView.
This study reveals that Testosterone–Androgen Receptor signaling delays elderly male bone destruction by upregulation of the osteoblastic extracellular tenascin‐C (TNC). The osteoprotective effect of fibrinogen C‐terminus of TNC is demonstrated in male osteoporotic mice model that osteoblast‐specific Ar‐knockout, potentially via inhibition of ...
Yong Xie, Meng Pan, Zeyuan Zhang, Licheng Zhang, Haotian Liu, Xia Wang, William W Lu, Peifu Tang, Wei Ge   +8 more
wiley   +1 more source

Experimental models for developing oncolytic virotherapy for metastatic prostate cancer. [PDF]

Front Immunol
Chen YC, Figueiredo ML.
europepmc   +1 more source

Evaluation of human papillomavirus as a risk factor in prostate cancer pathogenesis. [PDF]

Discov Oncol
Maliye R, Babu S, Harris AE, Patke R, Ntekim AI, Rutland CS, James V, Mongan NP, Madhusudan S, Jeyapalan JN, Semenova MM.   +10 more
europepmc   +1 more source

Prostate Cancer With Orbital Metastasis. [PDF]

Cureus
Gopishetty S, Singh L, Aqil M, Elhalis A, Ezekwudo D.   +4 more
europepmc   +1 more source

CAF-mediated regulation of prostate cancer stem cell stemness via the Wnt/β-catenin and SDF-1/CXCR4 pathways in castration-resistant prostate cancer. [PDF]

Front Cell Dev Biol
Chen H, Li Z, Yue Y, Zhu X, Wang J, Chen Y, Wang Y, Luo Z, Liu H.   +8 more
europepmc   +1 more source