Results 331 to 340 of about 5,889,184 (390)

Pirin Transcriptionally Regulates PLA2G4A To Inhibit Ferroptosis in Colorectal Cancer via Lipid Profile Remodeling

Advanced Science, EarlyView.
This study identifies Pirin (PIR), an iron‐binding protein, as a critical ferroptosis suppressor in colorectal cancer through lipid membrane remodeling. PIR, induced by NRF2 during ferroptotic stress, transcriptionally regulates PLA2G4A to shift cellular lipid composition away from ferroptosis‐permissive polyunsaturated phospholipids.
Wei Shi, Yue Qi Ong, Prativa Majee, Esther SM Wong, Amhed Missael Vargas Velazquez, Kerem Fidan, Pierce Kah‐Hoe Chow, Wai Leong Tam, Ker Kan Tan, Iain Beehuat Tan, Vinay Tergaonkar   +10 more
wiley   +1 more source

Tumor Cholesterol Synthesis, Statin Use, and Lethal Prostate Cancer. [PDF]

Mol Cancer Res
Flanagan S, Lis RT, Huang Y, Jehane L, Vaselkiv JB, Allott EH, Finn SP, Lotan TL, Fiorentino M, Loda M, Lee GM, Chakraborty G, Kantoff PW, Mucci LA, Stopsack KH.   +14 more
europepmc   +1 more source

PACT is requisite for prostate cancer cell proliferation. [PDF]

Sci Rep
Beveridge DJ, Woo AJ, Richardson KL, Brown RAM, Stuart LM, Singh M, Redfern AD, Leedman PJ.   +7 more
europepmc   +1 more source

20 years of taxane therapy in prostate cancer - the past, present and future. [PDF]

Nat Rev Urol
Carceles-Cordon M, Rodriguez-Bravo V, Petrylak DP, Domingo-Domenech J.   +3 more
europepmc   +1 more source

Measurement of patients' acceptable symptom levels and priorities for symptom improvement in advanced prostate cancer. [PDF]

Support Care Cancer
Snyder S, Secinti E, Krueger EF, Adra N, Pili R, Hanna NH, Mosher CE.   +6 more
europepmc   +1 more source

The natural history of prostate cancer. [PDF]

Can Urol Assoc J
O'Connell C, Bernardino RM, Fleshner NE.
europepmc   +1 more source