Results 171 to 180 of about 80,911 (249)

Allosteric coupling between a lipid bilayer and a membrane protein. [PDF]

Biophys J
Fourel C, Gautier Y, Pozza A, Giraud F, Point E, Le Bon C, Moncoq K, Stirnemann G, Hénin J, Lescop E, Catoire LJ.   +10 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Crystal structure of the virulence protein J (VirJ) domain 1 from Brucella abortus. [PDF]

Acta Crystallogr F Struct Biol Commun
Dugelay C, Ferrarin S, Terradot L.
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Tuberculous Meningitis Genetic predisposition: Understanding cellular interactions, molecular mechanisms and genetic dimensions. [PDF]

Tunis Med
Majambere JC, Zaidi S, Errami A, Marih L, Marhoum El Filali K, Bousfiha AA, Lahsen AO.   +6 more
europepmc   +1 more source

Les régimes alimentaires dans les pays tropicaux [PDF]

, 1974
Frontier-Abou, Danièle
core  

Dynamique d’assemblage des machineries nucléolaires après la mitose, en temps réel et en cellules vivantes [PDF]

, 2005
Hernandez-Verdun, Danièle
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

TTCT 1471 mutation in lysnuric protein intolerance: Clinical features of a Tunisian paediatric series. [PDF]

Tunis Med
Jbebli E, Jbeli Y, Amdouni R, Ben Abdelaziz R, Boudabous H, Ben Chehida A, Abdelmoula S.   +6 more
europepmc   +1 more source

Peri-urban small livestock production in the Kingdom of Cambodia : Biosecurity in poultry production in Phnom Penh [PDF]

, 2003
Porphyre, Vincent
core